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• W1996459873 abstract "A series of N-pyrimidinyl-2-phenoxyacetamide adenosine A2A antagonists is described. SAR studies led to compound 14 with excellent potency (Ki = 0.4 nM), selectivity (A1/A2A > 100), and efficacy (MED 10 mg/kg po) in the rat haloperidol-induced catalepsy model for Parkinson’s disease." @default.
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• W1996459873 date "2008-03-01" @default.
• W1996459873 modified "2023-10-18" @default.
• W1996459873 title "Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists" @default.
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• W1996459873 doi "https://doi.org/10.1016/j.bmcl.2008.02.032" @default.
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