FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996465629> ?p ?o ?g. }

• W1996465629 endingPage "286" @default.
• W1996465629 startingPage "261" @default.
• W1996465629 abstract "In order to evaluate the reproductive risks of low-frequency electromagnetic fields (EMF), it is important to include epidemiological and animal studies in the evaluation, as well as the appropriate basic science information in developmental biology and teratology. This review presents a critical review of in vivo animal studies and in vitro tests, as well as the biological plausibility of the allegations of reproductive risks. In vitro or in vivo studies in nonhuman species can be used to study mechanisms and the effects that have been suggested by human investigations. Only well designed whole-animal teratology studies are appropriate when the epidemiologists and clinical teratologists are uncertain about the environmental risks. Even the inference of teratogenesis cannot be drawn from culture experiments, because the investigator is not in a position to know whether any of his observations will be manifested in living organisms at term. Other aspects of reproductive failure such as abortion, infertility, stillbirth, and prematurity, cannot be addressed by in vitro or culture experiments. In fact, they are very difficult to design and interpret in nonprimate in vivo models. The biological plausibility some of the basic mechanisms involved in reproductive pathology were evaluated, concentrating primarily on the mechanisms involved in the production of birth defects. The studies dealing with mutagenesis, cell death and cell proliferation using in vitro systems do not indicate that EMFs have the potential for deleteriously affecting proliferating and differentiating embryonic cells at the exposures to which populations are usually exposed. Of course, there is no environmental agent that has no effect, deleterious or not, at very high exposures. The animal and in vitro studies dealing with the reproductive effects of EMF exposure are extensive. There are >70 EMF research projects that deal with some aspect of reproduction and growth. Unfortunately, a large proportion of the embryology studies used the chick embryo and evaluated the presence or absence of teratogenesis after 48–52 h of development. This is not a stage of development at which an investigator could determine whether teratogenesis occurred. The presence of clinically relevant teratogenesis can only be determined at the end of the gestational period. The chick embryo studies are also of little assistance to the epidemiologist or clinician in determining whether EMF represents a hazard to the human embryo, and the results are, in any event, inconsistent. On the other hand, the studies involving nonhuman mammalian organisms dealing with fetal growth, congenital malformations, embryonic loss, and neurobehavioral development were predominantly negative and are therefore not supportive of the hypothesis that low-frequency EMF exposures result in reproductive toxicity. Teratology 59:261–286, 1999. © 1999 Wiley-Liss, Inc." @default.
• W1996465629 created "2016-06-24" @default.
• W1996465629 creator A5038718789 @default.
• W1996465629 date "1999-04-01" @default.
• W1996465629 modified "2023-09-27" @default.
• W1996465629 title "Reproductive and teratologic effects of low-frequency electromagnetic fields: A review of in vivo and in vitro studies using animal models" @default.
• W1996465629 cites W138534537 @default.
• W1996465629 cites W1516972175 @default.
• W1996465629 cites W1526283956 @default.
• W1996465629 cites W1539435228 @default.
• W1996465629 cites W1595063804 @default.
• W1996465629 cites W193717996 @default.
• W1996465629 cites W1964242065 @default.
• W1996465629 cites W1969657234 @default.
• W1996465629 cites W1971907864 @default.
• W1996465629 cites W1973907943 @default.
• W1996465629 cites W1975130879 @default.
• W1996465629 cites W1976579288 @default.
• W1996465629 cites W1978689369 @default.
• W1996465629 cites W1979422406 @default.
• W1996465629 cites W1982144385 @default.
• W1996465629 cites W1985849802 @default.
• W1996465629 cites W1988631146 @default.
• W1996465629 cites W1992400222 @default.
• W1996465629 cites W1993129124 @default.
• W1996465629 cites W1993938729 @default.
• W1996465629 cites W1998029465 @default.
• W1996465629 cites W2003577462 @default.
• W1996465629 cites W2003898462 @default.
• W1996465629 cites W2006576936 @default.
• W1996465629 cites W2006822987 @default.
• W1996465629 cites W2007480944 @default.
• W1996465629 cites W2008382986 @default.
• W1996465629 cites W2013621535 @default.
• W1996465629 cites W2014820610 @default.
• W1996465629 cites W2015202549 @default.
• W1996465629 cites W2015534814 @default.
• W1996465629 cites W2016674909 @default.
• W1996465629 cites W2017560313 @default.
• W1996465629 cites W2018365429 @default.
• W1996465629 cites W2021375626 @default.
• W1996465629 cites W2021965516 @default.
• W1996465629 cites W2025011659 @default.
• W1996465629 cites W2025838115 @default.
• W1996465629 cites W2026223662 @default.
• W1996465629 cites W2034145097 @default.
• W1996465629 cites W2036233385 @default.
• W1996465629 cites W2037417797 @default.
• W1996465629 cites W2039002407 @default.
• W1996465629 cites W2040001232 @default.
• W1996465629 cites W2040110852 @default.
• W1996465629 cites W2040296964 @default.
• W1996465629 cites W2040544690 @default.
• W1996465629 cites W2042355277 @default.
• W1996465629 cites W2042828324 @default.
• W1996465629 cites W2046433073 @default.
• W1996465629 cites W2046498640 @default.
• W1996465629 cites W2047231663 @default.
• W1996465629 cites W2048366476 @default.
• W1996465629 cites W2053501663 @default.
• W1996465629 cites W2055375646 @default.
• W1996465629 cites W2057306466 @default.
• W1996465629 cites W2057735116 @default.
• W1996465629 cites W2057739487 @default.
• W1996465629 cites W2058595088 @default.
• W1996465629 cites W2060359290 @default.
• W1996465629 cites W2061020575 @default.
• W1996465629 cites W2062269718 @default.
• W1996465629 cites W2062523242 @default.
• W1996465629 cites W2063898190 @default.
• W1996465629 cites W2064873902 @default.
• W1996465629 cites W2069809199 @default.
• W1996465629 cites W2086925272 @default.
• W1996465629 cites W2088710431 @default.
• W1996465629 cites W2089051286 @default.
• W1996465629 cites W2089075683 @default.
• W1996465629 cites W2095057355 @default.
• W1996465629 cites W2095347979 @default.
• W1996465629 cites W2100121535 @default.
• W1996465629 cites W2112876173 @default.
• W1996465629 cites W2114136392 @default.
• W1996465629 cites W2118794417 @default.
• W1996465629 cites W2127017138 @default.
• W1996465629 cites W2137447467 @default.
• W1996465629 cites W2139583454 @default.
• W1996465629 cites W2146778637 @default.
• W1996465629 cites W2148419739 @default.
• W1996465629 cites W2149601981 @default.
• W1996465629 cites W2152364438 @default.
• W1996465629 cites W2177269273 @default.
• W1996465629 cites W2418264233 @default.
• W1996465629 cites W4256123115 @default.
• W1996465629 cites W996675263 @default.
• W1996465629 doi "https://doi.org/10.1002/(sici)1096-9926(199904)59:4<261::aid-tera12>3.0.co;2-k" @default.
• W1996465629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10331529" @default.
• W1996465629 hasPublicationYear "1999" @default.
• W1996465629 type Work @default.
• W1996465629 sameAs 1996465629 @default.

• next