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- W1996481329 abstract "The fine and gross motor activity of mice was measured at 1-minute intervals for 15 minutes after intravenous administration of ethanol or acetaldehyde. Acetaldehyde transiently reduced both types of motor activity whereas the effects of ethanol were more prolonged. The 1-minute ED50 values for depression of fine and gross activity by acetaldehyde are 2.2. and 2.7 mg/kg, respectively. The corresponding values for ethanol are 740 and 516 mg/kg. The differences in relative potencies became smaller as the time interval over which activity was measured increased. Thus, the potency of acetaldehyde as a depressant of behavior relative to ethanol is considerably greater than has previously been reported if effects are determined immediately after drug administration." @default.
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- W1996481329 date "1974-04-01" @default.
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- W1996481329 title "Comparison of acetaldehyde and ethanol: Depression of motor activity in mice" @default.
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- W1996481329 doi "https://doi.org/10.1016/0024-3205(74)90432-9" @default.
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