FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996502644> ?p ?o ?g. }

• W1996502644 abstract "FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows complex scenarios of selection, demography, and recombination to be modelled simultaneously. Detailed tracking of sites under selection is implemented in FREGENE and provides the opportunity to test theoretical predictions and gain new insights into mechanisms of selection. We describe here main functionalities of both FREGENE and SAMPLE, a companion program that can replicate association study datasets. We report detailed analyses of six large simulated datasets that we have made publicly available. Three demographic scenarios are modelled: one panmictic, one substructured with migration, and one complex scenario that mimics the principle features of genetic variation in major worldwide human populations. For each scenario there is one neutral simulation, and one with a complex pattern of selection. FREGENE and the simulated datasets will be valuable for assessing the validity of models for selection, demography and population genetic parameters, as well as the efficacy of association studies. Its principle advantages are modelling flexibility and computational efficiency. It is open source and object-oriented. As such, it can be customised and the range of models extended." @default.
• W1996502644 created "2016-06-24" @default.
• W1996502644 creator A5004028660 @default.
• W1996502644 creator A5041079153 @default.
• W1996502644 creator A5050004764 @default.
• W1996502644 creator A5077954390 @default.
• W1996502644 creator A5080254470 @default.
• W1996502644 creator A5091504243 @default.
• W1996502644 date "2008-09-08" @default.
• W1996502644 modified "2023-10-09" @default.
• W1996502644 title "Fregene: Simulation of realistic sequence-level data in populations and ascertained samples" @default.
• W1996502644 cites W1964853169 @default.
• W1996502644 cites W1969546066 @default.
• W1996502644 cites W1987299572 @default.
• W1996502644 cites W2013524758 @default.
• W1996502644 cites W2048980311 @default.
• W1996502644 cites W2104690544 @default.
• W1996502644 cites W2124300302 @default.
• W1996502644 cites W2151773637 @default.
• W1996502644 cites W2161644980 @default.
• W1996502644 cites W2165794141 @default.
• W1996502644 doi "https://doi.org/10.1186/1471-2105-9-364" @default.
• W1996502644 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2542380" @default.
• W1996502644 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18778480" @default.
• W1996502644 hasPublicationYear "2008" @default.
• W1996502644 type Work @default.
• W1996502644 sameAs 1996502644 @default.
• W1996502644 citedByCount "69" @default.
• W1996502644 countsByYear W19965026442012 @default.
• W1996502644 countsByYear W19965026442013 @default.
• W1996502644 countsByYear W19965026442014 @default.
• W1996502644 countsByYear W19965026442015 @default.
• W1996502644 countsByYear W19965026442016 @default.
• W1996502644 countsByYear W19965026442017 @default.
• W1996502644 countsByYear W19965026442018 @default.
• W1996502644 countsByYear W19965026442019 @default.
• W1996502644 countsByYear W19965026442020 @default.
• W1996502644 countsByYear W19965026442021 @default.
• W1996502644 countsByYear W19965026442022 @default.
• W1996502644 crossrefType "journal-article" @default.
• W1996502644 hasAuthorship W1996502644A5004028660 @default.
• W1996502644 hasAuthorship W1996502644A5041079153 @default.
• W1996502644 hasAuthorship W1996502644A5050004764 @default.
• W1996502644 hasAuthorship W1996502644A5077954390 @default.
• W1996502644 hasAuthorship W1996502644A5080254470 @default.
• W1996502644 hasAuthorship W1996502644A5091504243 @default.
• W1996502644 hasBestOaLocation W19965026441 @default.
• W1996502644 hasConcept C104317684 @default.
• W1996502644 hasConcept C105795698 @default.
• W1996502644 hasConcept C119857082 @default.
• W1996502644 hasConcept C124101348 @default.
• W1996502644 hasConcept C144024400 @default.
• W1996502644 hasConcept C149923435 @default.
• W1996502644 hasConcept C185592680 @default.
• W1996502644 hasConcept C193252679 @default.
• W1996502644 hasConcept C198531522 @default.
• W1996502644 hasConcept C2554327 @default.
• W1996502644 hasConcept C2780598303 @default.
• W1996502644 hasConcept C2781162219 @default.
• W1996502644 hasConcept C2908647359 @default.
• W1996502644 hasConcept C33923547 @default.
• W1996502644 hasConcept C41008148 @default.
• W1996502644 hasConcept C43617362 @default.
• W1996502644 hasConcept C54355233 @default.
• W1996502644 hasConcept C81917197 @default.
• W1996502644 hasConcept C86803240 @default.
• W1996502644 hasConceptScore W1996502644C104317684 @default.
• W1996502644 hasConceptScore W1996502644C105795698 @default.
• W1996502644 hasConceptScore W1996502644C119857082 @default.
• W1996502644 hasConceptScore W1996502644C124101348 @default.
• W1996502644 hasConceptScore W1996502644C144024400 @default.
• W1996502644 hasConceptScore W1996502644C149923435 @default.
• W1996502644 hasConceptScore W1996502644C185592680 @default.
• W1996502644 hasConceptScore W1996502644C193252679 @default.
• W1996502644 hasConceptScore W1996502644C198531522 @default.
• W1996502644 hasConceptScore W1996502644C2554327 @default.
• W1996502644 hasConceptScore W1996502644C2780598303 @default.
• W1996502644 hasConceptScore W1996502644C2781162219 @default.
• W1996502644 hasConceptScore W1996502644C2908647359 @default.
• W1996502644 hasConceptScore W1996502644C33923547 @default.
• W1996502644 hasConceptScore W1996502644C41008148 @default.
• W1996502644 hasConceptScore W1996502644C43617362 @default.
• W1996502644 hasConceptScore W1996502644C54355233 @default.
• W1996502644 hasConceptScore W1996502644C81917197 @default.
• W1996502644 hasConceptScore W1996502644C86803240 @default.
• W1996502644 hasIssue "1" @default.
• W1996502644 hasLocation W19965026441 @default.
• W1996502644 hasLocation W19965026442 @default.
• W1996502644 hasLocation W19965026443 @default.
• W1996502644 hasLocation W19965026444 @default.
• W1996502644 hasLocation W19965026445 @default.
• W1996502644 hasLocation W19965026446 @default.
• W1996502644 hasLocation W19965026447 @default.
• W1996502644 hasLocation W19965026448 @default.
• W1996502644 hasOpenAccess W1996502644 @default.
• W1996502644 hasPrimaryLocation W19965026441 @default.
• W1996502644 hasRelatedWork W1965062432 @default.
• W1996502644 hasRelatedWork W2027327351 @default.
• W1996502644 hasRelatedWork W2081951440 @default.
• W1996502644 hasRelatedWork W2094804172 @default.

• next