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- W1996532249 abstract "High platelet reactivity (HPR) is an established risk factor for ischemic complications after percutaneous coronary intervention (PCI) [ [1] Bonello L. Tantry U.S. Marcucci R. et al. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J. Am. Coll. Cardiol. 2010; 56: 919-933 Abstract Full Text Full Text PDF PubMed Scopus (1002) Google Scholar ], and low-responders to P2Y12 receptor antagonists have an increased risk of peri-procedural myonecrosis [ [2] Mangiacapra F. Barbato E. Patti G. et al. Point-of-care assessment of platelet reactivity after clopidogrel to predict myonecrosis in patients undergoing percutaneous coronary intervention. JACC Cardiovasc. Interv. 2010; 3: 318-323 Abstract Full Text Full Text PDF PubMed Scopus (56) Google Scholar ]. Numerous definitions have been proposed over the last few years for HPR [ [1] Bonello L. Tantry U.S. Marcucci R. et al. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J. Am. Coll. Cardiol. 2010; 56: 919-933 Abstract Full Text Full Text PDF PubMed Scopus (1002) Google Scholar ], as well as for PCI-related myocardial infarction (PMI) [ 3 Thygesen K. Alpert J.S. White H.D. Universal definition of myocardial infarction. J. Am. Coll. Cardiol. 2007; 50: 2173-2195 Abstract Full Text Full Text PDF PubMed Scopus (1491) Google Scholar , 4 Thygesen K. Alpert J.S. Jaffe A.S. et al. Third universal definition of myocardial infarction. J. Am. Coll. Cardiol. 2012; 60: 1581-1598 Abstract Full Text Full Text PDF PubMed Scopus (2220) Google Scholar , 5 Moussa I.D. Klein L.W. Shah B. et al. Consideration of a new definition of clinically relevant myocardial infarction after coronary revascularization: an expert consensus document from the Society for Cardiovascular Angiography and Interventions (SCAI). J. Am. Coll. Cardiol. 2013; 62: 1563-1570 Abstract Full Text Full Text PDF PubMed Scopus (409) Google Scholar ]. As a consequence, the incidence of both HPR and PMI can vary widely according to definitions, which may lead to confusion especially when exploring correlations and comparing trial results. Therefore, we sought to reappraise the association between HPR and PMI in the light of the several available definitions." @default.
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- W1996532249 date "2015-07-01" @default.
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- W1996532249 title "High platelet reactivity and periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention: A significant association beyond definitions" @default.
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- W1996532249 doi "https://doi.org/10.1016/j.ijcard.2015.04.158" @default.
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