FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996535143> ?p ?o ?g. }

• W1996535143 endingPage "3222" @default.
• W1996535143 startingPage "3215" @default.
• W1996535143 abstract "The ability of Listeria monocytogenes to invade non-phagocytic cells is important for development of a systemic listeriosis infection. The authors previously reported that a L. monocytogenes Δ sigB strain is defective in invasion into human intestinal epithelial cells, in part, due to decreased expression of a major invasion gene, inlA . To characterize additional invasion mechanisms under the control of σ B , mutants were generated carrying combinations of in-frame deletions in inlA , inlB and sigB . Quantitative assessment of bacterial invasion into the human enterocyte Caco-2 and hepatocyte HepG-2 cell lines demonstrated that σ B contributes to both InlA and InlB-mediated invasion of L. monocytogenes . Previous identification of the σ B -dependent P2 prfA promoter upstream of the major virulence gene regulator, positive regulatory factor A (PrfA), suggested that the contributions of σ B to expression of various virulence genes, including inlA , could be at least partially mediated through PrfA. To test this hypothesis, relative invasion capabilities of Δ sigB and Δ prfA strains were compared. Exponential-phase cells of the Δ sigB and Δ prfA strains were similarly defective at invasion; however, stationary-phase Δ sigB cells were significantly less invasive than stationary-phase Δ prfA cells, suggesting that the contributions of σ B to invasion extend beyond those mediated through PrfA in stationary-phase L. monocytogenes . TaqMan quantitative reverse-transcriptase PCRs further demonstrated that expression of inlA and inlB was greatly increased in a σ B -dependent manner in stationary-phase L. monocytogenes . Together, results from this study provide strong biological evidence of a critical role for σ B in L. monocytogenes invasion into non-phagocytic cells, primarily mediated through control of inlA and inlB expression." @default.
• W1996535143 created "2016-06-24" @default.
• W1996535143 creator A5033699998 @default.
• W1996535143 creator A5034076005 @default.
• W1996535143 creator A5065652234 @default.
• W1996535143 date "2005-10-01" @default.
• W1996535143 modified "2023-10-16" @default.
• W1996535143 title "σ B contributes to Listeria monocytogenes invasion by controlling expression of inlA and inlB" @default.
• W1996535143 cites W1505016159 @default.
• W1996535143 cites W1549831375 @default.
• W1996535143 cites W1784096314 @default.
• W1996535143 cites W1828550672 @default.
• W1996535143 cites W1892225881 @default.
• W1996535143 cites W1896823333 @default.
• W1996535143 cites W1909750055 @default.
• W1996535143 cites W1960902446 @default.
• W1996535143 cites W1968000268 @default.
• W1996535143 cites W1977141229 @default.
• W1996535143 cites W1990548600 @default.
• W1996535143 cites W1990677905 @default.
• W1996535143 cites W1996490581 @default.
• W1996535143 cites W2001553481 @default.
• W1996535143 cites W2032932328 @default.
• W1996535143 cites W2042181517 @default.
• W1996535143 cites W2044256998 @default.
• W1996535143 cites W2055351624 @default.
• W1996535143 cites W2060913542 @default.
• W1996535143 cites W2076198022 @default.
• W1996535143 cites W2080928558 @default.
• W1996535143 cites W2093417734 @default.
• W1996535143 cites W2095214726 @default.
• W1996535143 cites W2100017680 @default.
• W1996535143 cites W2103326203 @default.
• W1996535143 cites W2103719009 @default.
• W1996535143 cites W2109177577 @default.
• W1996535143 cites W2109847239 @default.
• W1996535143 cites W2111310696 @default.
• W1996535143 cites W2113539024 @default.
• W1996535143 cites W2114967795 @default.
• W1996535143 cites W2116401204 @default.
• W1996535143 cites W2125419801 @default.
• W1996535143 cites W2126569085 @default.
• W1996535143 cites W2130487625 @default.
• W1996535143 cites W2140917849 @default.
• W1996535143 cites W2141462914 @default.
• W1996535143 cites W2142036182 @default.
• W1996535143 cites W2152187506 @default.
• W1996535143 cites W2154895476 @default.
• W1996535143 doi "https://doi.org/10.1099/mic.0.28070-0" @default.
• W1996535143 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5857202" @default.
• W1996535143 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16207905" @default.
• W1996535143 hasPublicationYear "2005" @default.
• W1996535143 type Work @default.
• W1996535143 sameAs 1996535143 @default.
• W1996535143 citedByCount "126" @default.
• W1996535143 countsByYear W19965351432012 @default.
• W1996535143 countsByYear W19965351432013 @default.
• W1996535143 countsByYear W19965351432014 @default.
• W1996535143 countsByYear W19965351432015 @default.
• W1996535143 countsByYear W19965351432016 @default.
• W1996535143 countsByYear W19965351432017 @default.
• W1996535143 countsByYear W19965351432018 @default.
• W1996535143 countsByYear W19965351432019 @default.
• W1996535143 countsByYear W19965351432020 @default.
• W1996535143 countsByYear W19965351432021 @default.
• W1996535143 countsByYear W19965351432022 @default.
• W1996535143 countsByYear W19965351432023 @default.
• W1996535143 crossrefType "journal-article" @default.
• W1996535143 hasAuthorship W1996535143A5033699998 @default.
• W1996535143 hasAuthorship W1996535143A5034076005 @default.
• W1996535143 hasAuthorship W1996535143A5065652234 @default.
• W1996535143 hasBestOaLocation W19965351431 @default.
• W1996535143 hasConcept C101762097 @default.
• W1996535143 hasConcept C104317684 @default.
• W1996535143 hasConcept C11957725 @default.
• W1996535143 hasConcept C150194340 @default.
• W1996535143 hasConcept C2776415932 @default.
• W1996535143 hasConcept C2781090273 @default.
• W1996535143 hasConcept C2781350384 @default.
• W1996535143 hasConcept C47319516 @default.
• W1996535143 hasConcept C523546767 @default.
• W1996535143 hasConcept C54355233 @default.
• W1996535143 hasConcept C60987743 @default.
• W1996535143 hasConcept C86803240 @default.
• W1996535143 hasConcept C89423630 @default.
• W1996535143 hasConceptScore W1996535143C101762097 @default.
• W1996535143 hasConceptScore W1996535143C104317684 @default.
• W1996535143 hasConceptScore W1996535143C11957725 @default.
• W1996535143 hasConceptScore W1996535143C150194340 @default.
• W1996535143 hasConceptScore W1996535143C2776415932 @default.
• W1996535143 hasConceptScore W1996535143C2781090273 @default.
• W1996535143 hasConceptScore W1996535143C2781350384 @default.
• W1996535143 hasConceptScore W1996535143C47319516 @default.
• W1996535143 hasConceptScore W1996535143C523546767 @default.
• W1996535143 hasConceptScore W1996535143C54355233 @default.
• W1996535143 hasConceptScore W1996535143C60987743 @default.
• W1996535143 hasConceptScore W1996535143C86803240 @default.
• W1996535143 hasConceptScore W1996535143C89423630 @default.

• next