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- W1996538257 abstract "An increased prevalence of atopy has been observed in patients with cross-intolerance to NSAIDs. This association has been observed between inhalant allergens (house dust mites) and different clinical manifestations of cross-intolerance to NSAIDs (i.e. acute urticaria/angioedema). Whether an association exists with food allergens has not been assessed. The aim of this study was to investigate sensitization to a wide panel of food allergens in patients diagnosed as acute urticaria/angioedema induced by cross-intolerance to NSAIDs (AUA). Patients with confirmed history of AUA (≥2 episodes with at least 2 different NSAIDs or positive drug provocation test), selective responders to NSAIDs (SR) and controls who tolerated NSAIDs were included. Skin prick tests were performed with a battery of 31 common food allergens that included animal, fruit and vegetable allergens. Specific IgE was determined in serum by ImmunoCAP, considering positive a value higher than 0,35 IU/mL. A total of 120 patients with confirmed history of AUA, 100 SR and 152 controls were studied. The 62.5% were females with a mean age 42.54±14.76 years. Positive skin tests and specific IgE in serum were detected in 4 (3,33%) patients AUA and in 7 (4,6%) controls (p>0,05). None of SR had positive tests. No differences were found in the allergens tested in both AUA and control groups. Food allergy is not a risk factor for developing AUA. Further studies are needed to confirm this finding." @default.
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- W1996538257 date "2013-02-01" @default.
- W1996538257 modified "2023-10-06" @default.
- W1996538257 title "Food Allergy Is Not A Risk Factor in Cross-Intolerance to Nsaids for Induction of Symptoms" @default.
- W1996538257 doi "https://doi.org/10.1016/j.jaci.2012.12.1260" @default.
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