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- W1996544436 abstract "It is generally agreed that the hypothalamus exerts some degree of control over the secretion of thyrotropic hormone (TSH) by the anterior pituitary. Experimental verification of this has been attempted in vitro by examining the ability of the hypothalamus to release TSH from pituitary fragments utilizing the assay described by Bakke et al. This assay is based upon an inhibition of weight loss of thyroid slices under the influence of TSH. Rabbit thyroid slices, after incubation alone, weighed 60.0±0.8% of the original weight. Up to 1,200 mg of diencephalic tissue containing the hypothalamus incubated with thyroid slices had no effect on this weight loss. One and one-half to 3.5 mg of anterior pituitary tissue incubated with thyroid slices inhibited weight loss to a minor degree, the final weight averaging 62.8±0.9% of the original weight. However, when amounts greater than 400–600 mg of diencephalon were incubated with a pituitary fragment, the thyroid slice weight loss was further inhibited and the final..." @default.
- W1996544436 created "2016-06-24" @default.
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- W1996544436 date "1963-01-01" @default.
- W1996544436 modified "2023-09-27" @default.
- W1996544436 title "In VitroInfluence of Central Nervous System Tissues on Thyrotropin Secretion" @default.
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- W1996544436 doi "https://doi.org/10.1210/endo-72-1-39" @default.
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