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• W1996569062 abstract "First weeks after alcohol withdrawal, associated with profound changes in neural transmission, constitute the critical period for relapse prevention and pharmacological intervention in alcoholism. Here, 20 male alcoholics with 1-6 weeks of abstinence and 20 age-matched healthy controls were studied using auditory event-related potentials (ERP), measured with a 32-channel electroencephalogram, and neuropsychological tests of auditory-verbal memory. Global field power maximum of ERP during 80-150 ms period after presentation of unattended tones (binaural 700 Hz pure tones, inter-stimulus interval 2.5 s) was significantly (P<0.01) larger in the alcoholics than controls. This effect, reflecting augmented N1 generation, significantly correlated (r=0.5) with impaired memory performance in the alcoholics. The profound change in pre-attentive auditory processing, predicting impaired memory performance, might reflect impaired cerebral inhibitory transmission in alcoholics." @default.
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• W1996569062 date "2000-05-01" @default.
• W1996569062 modified "2023-10-01" @default.
• W1996569062 title "Global field power of auditory N1 correlates with impaired verbal-memory performance in human alcoholics" @default.
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• W1996569062 doi "https://doi.org/10.1016/s0304-3940(00)01041-7" @default.
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