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- W1996596237 endingPage "123" @default.
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- W1996596237 abstract "Release of cytotoxic granule proteins from activated eosinophil granules is considered to be a key pathogenic mechanism in eosinophilic diseases. Degenerated eosinophils and extracellular eosinophil granules have been repeatedly depicted. The present overview describes evidence that eosinophil lysis and distribution of free eosinophil granules (as opposed to 'classical degranulation') is an important mechanism by which eosinophils affect their surroundings. Here, Carl Persson and Jonas Erjefält summarize how recent reports on the induction of eosinophil lysis in vivo provide a new paradigm for eosinophil activation and thus constitute a novel basis for pharmacological manipulations in eosinophilic diseases." @default.
- W1996596237 created "2016-06-24" @default.
- W1996596237 creator A5038367518 @default.
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- W1996596237 date "1997-07-01" @default.
- W1996596237 modified "2023-09-26" @default.
- W1996596237 title "Eosinophil lysis and free granules: an in vivo paradigm for cell activation and drug development" @default.
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- W1996596237 doi "https://doi.org/10.1016/s0165-6147(97)01042-0" @default.
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