SemOpenAlex |

SemOpenAlex

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996612349> ?p ?o ?g. }

Showing items 1 to 100 of ±128 with 100 items per page.

W1996612349 endingPage "216" @default.
W1996612349 startingPage "211" @default.
W1996612349 abstract "In order to examine the cadmium cytotoxicity unrelated to external Ca(2+), the effects of micromolar CdCl(2) on intracellular Cd(2+) concentration, cellular content of glutathione, and cell viability of rat cerebellar granule neurons were examined under normal Ca(2+) and external Ca(2+)-free conditions, using a laser confocal microscope with fluorescent probes, fluo-3-AM, 5-chloromethylfluorescein (CMF) diacetate, and propidium iodide. CdCl(2) (10-300 microM) dose-dependently increased the intensity of fluo-3 fluorescence. Exposure to CdCl(2) equally enhanced the fluo-3 fluorescence under both Ca(2+) conditions and MnCl(2) did not quench the CdCl(2)-enhanced fluorescence. The results indicate that the enhancement of fluo-3 fluorescence is due to the increase in intracellular Cd(2+) concentration. CdCl(2) at 100-300 microM decreased the intensity of CMF fluorescence, indicating the decrease in cellular content of glutathione. The population of cells stained with propidium (dead cells) was increased by 100-300 microM CdCl(2). Similar results described above were also observed under external Ca(2+)-free condition. It is suggested that some of cytotoxic actions of CdCl(2) on neurons are unrelated to external Ca(2+), one of main sources for increasing intracellular Ca(2+) concentration." @default.
W1996612349 created "2016-06-24" @default.
W1996612349 creator A5005436782 @default.
W1996612349 creator A5028257174 @default.
W1996612349 creator A5028981415 @default.
W1996612349 creator A5060700088 @default.
W1996612349 creator A5062440316 @default.
W1996612349 creator A5062571823 @default.
W1996612349 creator A5062970460 @default.
W1996612349 date "2006-03-01" @default.
W1996612349 modified "2023-09-24" @default.
W1996612349 title "Increase in intracellular Cd2+ concentration of rat cerebellar granule neurons incubated with cadmium chloride: Cadmium cytotoxicity under external Ca2+-free condition" @default.
W1996612349 cites W1529590189 @default.
W1996612349 cites W1563884529 @default.
W1996612349 cites W1798204859 @default.
W1996612349 cites W1968364218 @default.
W1996612349 cites W1972876027 @default.
W1996612349 cites W1989452037 @default.
W1996612349 cites W1989670509 @default.
W1996612349 cites W1992099243 @default.
W1996612349 cites W1997244673 @default.
W1996612349 cites W2003380222 @default.
W1996612349 cites W2005618732 @default.
W1996612349 cites W2008578486 @default.
W1996612349 cites W2017924999 @default.
W1996612349 cites W2028548029 @default.
W1996612349 cites W2029764326 @default.
W1996612349 cites W2037403444 @default.
W1996612349 cites W2043802562 @default.
W1996612349 cites W2047158259 @default.
W1996612349 cites W2047569630 @default.
W1996612349 cites W2055373230 @default.
W1996612349 cites W2067084274 @default.
W1996612349 cites W2068769123 @default.
W1996612349 cites W2070699739 @default.
W1996612349 cites W2077227893 @default.
W1996612349 cites W2087630663 @default.
W1996612349 cites W2112173647 @default.
W1996612349 cites W2126475226 @default.
W1996612349 cites W2150001323 @default.
W1996612349 cites W2151093371 @default.
W1996612349 cites W2158414814 @default.
W1996612349 cites W2171981975 @default.
W1996612349 cites W25159128 @default.
W1996612349 doi "https://doi.org/10.1016/j.tiv.2005.06.006" @default.
W1996612349 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16061347" @default.
W1996612349 hasPublicationYear "2006" @default.
W1996612349 type Work @default.
W1996612349 sameAs 1996612349 @default.
W1996612349 citedByCount "42" @default.
W1996612349 countsByYear W19966123492012 @default.
W1996612349 countsByYear W19966123492013 @default.
W1996612349 countsByYear W19966123492014 @default.
W1996612349 countsByYear W19966123492015 @default.
W1996612349 countsByYear W19966123492016 @default.
W1996612349 countsByYear W19966123492017 @default.
W1996612349 countsByYear W19966123492018 @default.
W1996612349 countsByYear W19966123492021 @default.
W1996612349 countsByYear W19966123492022 @default.
W1996612349 countsByYear W19966123492023 @default.
W1996612349 crossrefType "journal-article" @default.
W1996612349 hasAuthorship W1996612349A5005436782 @default.
W1996612349 hasAuthorship W1996612349A5028257174 @default.
W1996612349 hasAuthorship W1996612349A5028981415 @default.
W1996612349 hasAuthorship W1996612349A5060700088 @default.
W1996612349 hasAuthorship W1996612349A5062440316 @default.
W1996612349 hasAuthorship W1996612349A5062571823 @default.
W1996612349 hasAuthorship W1996612349A5062970460 @default.
W1996612349 hasConcept C121332964 @default.
W1996612349 hasConcept C12554922 @default.
W1996612349 hasConcept C144024400 @default.
W1996612349 hasConcept C149923435 @default.
W1996612349 hasConcept C178790620 @default.
W1996612349 hasConcept C181199279 @default.
W1996612349 hasConcept C185592680 @default.
W1996612349 hasConcept C190283241 @default.
W1996612349 hasConcept C2775934118 @default.
W1996612349 hasConcept C2778643788 @default.
W1996612349 hasConcept C2908647359 @default.
W1996612349 hasConcept C31573885 @default.
W1996612349 hasConcept C538909803 @default.
W1996612349 hasConcept C544657597 @default.
W1996612349 hasConcept C55493867 @default.
W1996612349 hasConcept C62520636 @default.
W1996612349 hasConcept C79879829 @default.
W1996612349 hasConcept C86803240 @default.
W1996612349 hasConcept C91881484 @default.
W1996612349 hasConceptScore W1996612349C121332964 @default.
W1996612349 hasConceptScore W1996612349C12554922 @default.
W1996612349 hasConceptScore W1996612349C144024400 @default.
W1996612349 hasConceptScore W1996612349C149923435 @default.
W1996612349 hasConceptScore W1996612349C178790620 @default.
W1996612349 hasConceptScore W1996612349C181199279 @default.
W1996612349 hasConceptScore W1996612349C185592680 @default.
W1996612349 hasConceptScore W1996612349C190283241 @default.
W1996612349 hasConceptScore W1996612349C2775934118 @default.
W1996612349 hasConceptScore W1996612349C2778643788 @default.
W1996612349 hasConceptScore W1996612349C2908647359 @default.