FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996632858> ?p ?o ?g. }

• W1996632858 abstract "Activation of cytokine receptors and alterations in cytokines are thought to play important roles in neuronal dysfunction and in the pathogenesis of the nervous system diseases. CXCL8 (IL-8) is a CXC chemokine with chemotactic and inflammatory properties. Chemokines control mast cell infiltration in several inflammatory diseases, including stress and neurological dysfunctions. Using isolated human umbilical cord blood-derived cultured mast cells (HUCMC) from hematopoietic stem cells CD34+, mast cells were immunologically activated with anti-IgE at concentrations of 1, 5, 10 and 20 microg/ml leading to the dose-dependent production of IL-8 (p < 0.05). The increase in IL-8 mRNA expression was also noted when the cells were treated with anti-IgE at 10 microg/ml for 6 h. Immunologically activated HUCMC provoked the generation of tryptase in a dose- and time-dependent manner. We also found increased histidine decarboxylase (HDC) expression in activated HUCMC after 6 h of incubation, a rate-limiting enzyme responsible for the generation of histamine from histidine. Taken together, these results confirm that anti-IgE-activated mast cells release inflammatory mediators including CXCL8, a CXC chemokine which regulates several biological effects of mast cells, e.g. chemoattraction, and possibly causes cell arrest." @default.
• W1996632858 created "2016-06-24" @default.
• W1996632858 creator A5001957324 @default.
• W1996632858 creator A5008521604 @default.
• W1996632858 creator A5009732833 @default.
• W1996632858 creator A5044759756 @default.
• W1996632858 creator A5053802252 @default.
• W1996632858 creator A5054106836 @default.
• W1996632858 creator A5056189217 @default.
• W1996632858 creator A5064540758 @default.
• W1996632858 creator A5075712214 @default.
• W1996632858 creator A5082352697 @default.
• W1996632858 creator A5084999451 @default.
• W1996632858 creator A5090207334 @default.
• W1996632858 date "2007-01-01" @default.
• W1996632858 modified "2023-10-16" @default.
• W1996632858 title "Expression and Secretion of CXCL8 (IL-8), Release of Tryptase and Transcription of Histidine Decarboxylase mRNA by Anti-IgE-Activated Human Umbilical Cord Blood-Derived Cultured Mast Cells" @default.
• W1996632858 cites W11235472 @default.
• W1996632858 cites W125667030 @default.
• W1996632858 cites W13143911 @default.
• W1996632858 cites W149583437 @default.
• W1996632858 cites W1524632935 @default.
• W1996632858 cites W153696494 @default.
• W1996632858 cites W1580512174 @default.
• W1996632858 cites W1586878534 @default.
• W1996632858 cites W158945528 @default.
• W1996632858 cites W1791079802 @default.
• W1996632858 cites W1974430704 @default.
• W1996632858 cites W198407752 @default.
• W1996632858 cites W2002519082 @default.
• W1996632858 cites W2012213345 @default.
• W1996632858 cites W2034108509 @default.
• W1996632858 cites W2047887530 @default.
• W1996632858 cites W2052797473 @default.
• W1996632858 cites W2079696887 @default.
• W1996632858 cites W2094469463 @default.
• W1996632858 cites W2122893474 @default.
• W1996632858 cites W2138000429 @default.
• W1996632858 cites W2140174247 @default.
• W1996632858 cites W2147087574 @default.
• W1996632858 cites W2233474262 @default.
• W1996632858 cites W2272566893 @default.
• W1996632858 cites W2281974748 @default.
• W1996632858 cites W2321044154 @default.
• W1996632858 cites W2340874390 @default.
• W1996632858 cites W2395770505 @default.
• W1996632858 cites W2396846501 @default.
• W1996632858 cites W2401770359 @default.
• W1996632858 cites W2402442408 @default.
• W1996632858 cites W2405281184 @default.
• W1996632858 cites W2409171745 @default.
• W1996632858 cites W2411389767 @default.
• W1996632858 cites W2416811279 @default.
• W1996632858 cites W2418272879 @default.
• W1996632858 cites W2439993272 @default.
• W1996632858 cites W2460204148 @default.
• W1996632858 cites W2461298592 @default.
• W1996632858 cites W2572020756 @default.
• W1996632858 cites W2572075110 @default.
• W1996632858 cites W2573925430 @default.
• W1996632858 cites W2573947439 @default.
• W1996632858 cites W2576140552 @default.
• W1996632858 cites W4253358906 @default.
• W1996632858 cites W4594968 @default.
• W1996632858 cites W72503002 @default.
• W1996632858 cites W89302952 @default.
• W1996632858 cites W2338475827 @default.
• W1996632858 doi "https://doi.org/10.1159/000107425" @default.
• W1996632858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17713357" @default.
• W1996632858 hasPublicationYear "2007" @default.
• W1996632858 type Work @default.
• W1996632858 sameAs 1996632858 @default.
• W1996632858 citedByCount "4" @default.
• W1996632858 countsByYear W19966328582012 @default.
• W1996632858 countsByYear W19966328582017 @default.
• W1996632858 crossrefType "journal-article" @default.
• W1996632858 hasAuthorship W1996632858A5001957324 @default.
• W1996632858 hasAuthorship W1996632858A5008521604 @default.
• W1996632858 hasAuthorship W1996632858A5009732833 @default.
• W1996632858 hasAuthorship W1996632858A5044759756 @default.
• W1996632858 hasAuthorship W1996632858A5053802252 @default.
• W1996632858 hasAuthorship W1996632858A5054106836 @default.
• W1996632858 hasAuthorship W1996632858A5056189217 @default.
• W1996632858 hasAuthorship W1996632858A5064540758 @default.
• W1996632858 hasAuthorship W1996632858A5075712214 @default.
• W1996632858 hasAuthorship W1996632858A5082352697 @default.
• W1996632858 hasAuthorship W1996632858A5084999451 @default.
• W1996632858 hasAuthorship W1996632858A5090207334 @default.
• W1996632858 hasConcept C122862929 @default.
• W1996632858 hasConcept C126322002 @default.
• W1996632858 hasConcept C13373296 @default.
• W1996632858 hasConcept C134018914 @default.
• W1996632858 hasConcept C141105273 @default.
• W1996632858 hasConcept C159654299 @default.
• W1996632858 hasConcept C170493617 @default.
• W1996632858 hasConcept C192233252 @default.
• W1996632858 hasConcept C203014093 @default.
• W1996632858 hasConcept C2776914184 @default.
• W1996632858 hasConcept C2778460671 @default.
• W1996632858 hasConcept C2778690821 @default.

• next