Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996648506> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1996648506 endingPage "465" @default.
- W1996648506 startingPage "457" @default.
- W1996648506 abstract "1. In slightly alkaline solutions of low ionic strength, actinomycin D, DNA and chymotrypsinogen A have been shown to form a kinetically stable triple complex which can be isolated by sucrose density gradient sedimentation or gel filtration. This triple complex does not appear to be any less stable than the respective actinomycin-DNA and chymotrypsinogen-DNA complexes. 2. Spectrophotometric data indicated that the binding capacity of DNA for actinomycin was not significantly affected by chymotrypsinogen-DNA binding. 3. No evidence was found for binding of actinomycin to the protein. 4. Both the antibiotic and the protein in the triple complex appeared to contribute to the increase in the DNA melting temperature. 5. The results of sucrose density gradient sedimentation are consistent with the current belief that actinomycin does not intercalate into the DNA helix. 6. If bound actinomycin is situated in the minor groove of DNA, the present results would indicate that chymotrypsinogen binding does not mask the minor groove to any great extent." @default.
- W1996648506 created "2016-06-24" @default.
- W1996648506 creator A5009626787 @default.
- W1996648506 date "1968-12-01" @default.
- W1996648506 modified "2023-10-17" @default.
- W1996648506 title "Interaction of actinomycin D with the chymotrypsinogen-DNA complex" @default.
- W1996648506 cites W156590816 @default.
- W1996648506 cites W1575179 @default.
- W1996648506 cites W1968505061 @default.
- W1996648506 cites W1984567542 @default.
- W1996648506 cites W1992704047 @default.
- W1996648506 cites W1995386269 @default.
- W1996648506 cites W1999799234 @default.
- W1996648506 cites W2001915752 @default.
- W1996648506 cites W2006019032 @default.
- W1996648506 cites W2014316343 @default.
- W1996648506 cites W2017249533 @default.
- W1996648506 cites W2029362994 @default.
- W1996648506 cites W2038228352 @default.
- W1996648506 cites W2040461510 @default.
- W1996648506 cites W2048437026 @default.
- W1996648506 cites W2067103174 @default.
- W1996648506 cites W2067878166 @default.
- W1996648506 cites W2069151276 @default.
- W1996648506 cites W2070441348 @default.
- W1996648506 cites W2075717102 @default.
- W1996648506 cites W2084761449 @default.
- W1996648506 cites W2090102372 @default.
- W1996648506 cites W2118543320 @default.
- W1996648506 cites W2174345790 @default.
- W1996648506 cites W2397173426 @default.
- W1996648506 doi "https://doi.org/10.1016/0005-2787(68)90054-3" @default.
- W1996648506 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5750459" @default.
- W1996648506 hasPublicationYear "1968" @default.
- W1996648506 type Work @default.
- W1996648506 sameAs 1996648506 @default.
- W1996648506 citedByCount "1" @default.
- W1996648506 crossrefType "journal-article" @default.
- W1996648506 hasAuthorship W1996648506A5009626787 @default.
- W1996648506 hasConcept C178790620 @default.
- W1996648506 hasConcept C181199279 @default.
- W1996648506 hasConcept C184651966 @default.
- W1996648506 hasConcept C185592680 @default.
- W1996648506 hasConcept C187428577 @default.
- W1996648506 hasConcept C206759300 @default.
- W1996648506 hasConcept C2778401398 @default.
- W1996648506 hasConcept C2778597767 @default.
- W1996648506 hasConcept C2780340462 @default.
- W1996648506 hasConcept C552990157 @default.
- W1996648506 hasConcept C55493867 @default.
- W1996648506 hasConceptScore W1996648506C178790620 @default.
- W1996648506 hasConceptScore W1996648506C181199279 @default.
- W1996648506 hasConceptScore W1996648506C184651966 @default.
- W1996648506 hasConceptScore W1996648506C185592680 @default.
- W1996648506 hasConceptScore W1996648506C187428577 @default.
- W1996648506 hasConceptScore W1996648506C206759300 @default.
- W1996648506 hasConceptScore W1996648506C2778401398 @default.
- W1996648506 hasConceptScore W1996648506C2778597767 @default.
- W1996648506 hasConceptScore W1996648506C2780340462 @default.
- W1996648506 hasConceptScore W1996648506C552990157 @default.
- W1996648506 hasConceptScore W1996648506C55493867 @default.
- W1996648506 hasIssue "2" @default.
- W1996648506 hasLocation W19966485061 @default.
- W1996648506 hasLocation W19966485062 @default.
- W1996648506 hasOpenAccess W1996648506 @default.
- W1996648506 hasPrimaryLocation W19966485061 @default.
- W1996648506 hasRelatedWork W1969462187 @default.
- W1996648506 hasRelatedWork W1985222651 @default.
- W1996648506 hasRelatedWork W2022888814 @default.
- W1996648506 hasRelatedWork W2087052575 @default.
- W1996648506 hasRelatedWork W2088967843 @default.
- W1996648506 hasRelatedWork W2110258898 @default.
- W1996648506 hasRelatedWork W2144709115 @default.
- W1996648506 hasRelatedWork W2399368498 @default.
- W1996648506 hasRelatedWork W2575981054 @default.
- W1996648506 hasRelatedWork W2627532858 @default.
- W1996648506 hasVolume "169" @default.
- W1996648506 isParatext "false" @default.
- W1996648506 isRetracted "false" @default.
- W1996648506 magId "1996648506" @default.
- W1996648506 workType "article" @default.