FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996648968> ?p ?o ?g. }

• W1996648968 endingPage "e1885" @default.
• W1996648968 startingPage "e1885" @default.
• W1996648968 abstract "Radioactive iodine is commonly administered following thyroidectomy for differentiated thyroid carcinoma to ablate the thyroid remnant. The optimal administered activity of radioiodine is unknown.Adult subjects (n = 160) diagnosed with papillary or follicular thyroid carcinoma were randomly allocated to receive either 1100 MBq (30 mCi) or 3700 MBq (100 mCi) activity of radioiodine ((131)I) following thyroidectomy. The study participants were prepared for ablation using thyroid hormone withdrawal. Ablation was considered successful when serum thyroglobulin concentration was less than 1 ng/mL and no uptake was present in (131)I scan. Ablation was successful following one administration of radioiodine in 42 (52%; 95% CI, 41% to 63%) of the 81 evaluable study participants who received 1100 MBq, and in 43 (56%, 45% to 67%) of the 77 subjects who received 3700 MBq activity (P = .61). There was no difference between the groups in the numbers of repeat radioiodine treatments needed to complete ablation (P = .27). The higher activity was associated with more nausea and taste disturbances, and a longer stay in a radioprotected isolation unit. None of the participants died from thyroid cancer during a median follow up of 51 months; three subjects in the 3700 MBq group and none in the 1100 MBq group were diagnosed with distant metastases during follow-up. In a meta-analysis of four randomized studies that compared the 1100 and 3700 MBq activities, the 1100 MBq activity tended to be associated with a higher risk of unsuccessful ablation (relative risk 1.148, 95% CI 0.974 to 1.353, P = .10).The results provide no conclusive evidence that 3700 MBq activity is more effective for ablation of the thyroid remnant than 1100 MBq activity. The 3700 MBq activity is associated with more adverse effects.ClinicalTrials.gov NCT00115895." @default.
• W1996648968 created "2016-06-24" @default.
• W1996648968 creator A5011490766 @default.
• W1996648968 creator A5014527740 @default.
• W1996648968 creator A5022282438 @default.
• W1996648968 creator A5046890841 @default.
• W1996648968 creator A5090618504 @default.
• W1996648968 date "2008-04-02" @default.
• W1996648968 modified "2023-10-12" @default.
• W1996648968 title "Low vs. High Radioiodine Activity to Ablate the Thyroid after Thyroidectomy for Cancer: A Randomized Study" @default.
• W1996648968 cites W1968467130 @default.
• W1996648968 cites W1968498828 @default.
• W1996648968 cites W1995343355 @default.
• W1996648968 cites W2005645290 @default.
• W1996648968 cites W2009925064 @default.
• W1996648968 cites W2028080080 @default.
• W1996648968 cites W2046470280 @default.
• W1996648968 cites W2080129399 @default.
• W1996648968 cites W2088828338 @default.
• W1996648968 cites W2095030807 @default.
• W1996648968 cites W2117971741 @default.
• W1996648968 cites W2121433489 @default.
• W1996648968 cites W2123915332 @default.
• W1996648968 cites W2151909232 @default.
• W1996648968 cites W2152653685 @default.
• W1996648968 cites W4211107646 @default.
• W1996648968 doi "https://doi.org/10.1371/journal.pone.0001885" @default.
• W1996648968 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2270902" @default.
• W1996648968 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18382668" @default.
• W1996648968 hasPublicationYear "2008" @default.
• W1996648968 type Work @default.
• W1996648968 sameAs 1996648968 @default.
• W1996648968 citedByCount "98" @default.
• W1996648968 countsByYear W19966489682012 @default.
• W1996648968 countsByYear W19966489682013 @default.
• W1996648968 countsByYear W19966489682014 @default.
• W1996648968 countsByYear W19966489682015 @default.
• W1996648968 countsByYear W19966489682016 @default.
• W1996648968 countsByYear W19966489682017 @default.
• W1996648968 countsByYear W19966489682018 @default.
• W1996648968 countsByYear W19966489682019 @default.
• W1996648968 countsByYear W19966489682020 @default.
• W1996648968 countsByYear W19966489682021 @default.
• W1996648968 countsByYear W19966489682022 @default.
• W1996648968 countsByYear W19966489682023 @default.
• W1996648968 crossrefType "journal-article" @default.
• W1996648968 hasAuthorship W1996648968A5011490766 @default.
• W1996648968 hasAuthorship W1996648968A5014527740 @default.
• W1996648968 hasAuthorship W1996648968A5022282438 @default.
• W1996648968 hasAuthorship W1996648968A5046890841 @default.
• W1996648968 hasAuthorship W1996648968A5090618504 @default.
• W1996648968 hasBestOaLocation W19966489681 @default.
• W1996648968 hasConcept C126322002 @default.
• W1996648968 hasConcept C126894567 @default.
• W1996648968 hasConcept C168563851 @default.
• W1996648968 hasConcept C2777074255 @default.
• W1996648968 hasConcept C2778835679 @default.
• W1996648968 hasConcept C2778902805 @default.
• W1996648968 hasConcept C2779341817 @default.
• W1996648968 hasConcept C2779761222 @default.
• W1996648968 hasConcept C2780580376 @default.
• W1996648968 hasConcept C2781461381 @default.
• W1996648968 hasConcept C2989005 @default.
• W1996648968 hasConcept C2993294228 @default.
• W1996648968 hasConcept C526584372 @default.
• W1996648968 hasConcept C71924100 @default.
• W1996648968 hasConceptScore W1996648968C126322002 @default.
• W1996648968 hasConceptScore W1996648968C126894567 @default.
• W1996648968 hasConceptScore W1996648968C168563851 @default.
• W1996648968 hasConceptScore W1996648968C2777074255 @default.
• W1996648968 hasConceptScore W1996648968C2778835679 @default.
• W1996648968 hasConceptScore W1996648968C2778902805 @default.
• W1996648968 hasConceptScore W1996648968C2779341817 @default.
• W1996648968 hasConceptScore W1996648968C2779761222 @default.
• W1996648968 hasConceptScore W1996648968C2780580376 @default.
• W1996648968 hasConceptScore W1996648968C2781461381 @default.
• W1996648968 hasConceptScore W1996648968C2989005 @default.
• W1996648968 hasConceptScore W1996648968C2993294228 @default.
• W1996648968 hasConceptScore W1996648968C526584372 @default.
• W1996648968 hasConceptScore W1996648968C71924100 @default.
• W1996648968 hasIssue "4" @default.
• W1996648968 hasLocation W19966489681 @default.
• W1996648968 hasLocation W19966489682 @default.
• W1996648968 hasLocation W19966489683 @default.
• W1996648968 hasLocation W19966489684 @default.
• W1996648968 hasLocation W19966489685 @default.
• W1996648968 hasLocation W19966489686 @default.
• W1996648968 hasOpenAccess W1996648968 @default.
• W1996648968 hasPrimaryLocation W19966489681 @default.
• W1996648968 hasRelatedWork W1853885143 @default.
• W1996648968 hasRelatedWork W1981090278 @default.
• W1996648968 hasRelatedWork W1988357267 @default.
• W1996648968 hasRelatedWork W2030286795 @default.
• W1996648968 hasRelatedWork W2153521617 @default.
• W1996648968 hasRelatedWork W2168268608 @default.
• W1996648968 hasRelatedWork W2375126294 @default.
• W1996648968 hasRelatedWork W2418684463 @default.
• W1996648968 hasRelatedWork W2440959534 @default.

• next