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- W1996683618 abstract "In continuance of our search for newer anti-cancer agents we were interested on embelin, a XIAP (X-linked inhibitor of apoptosis protein) inhibitor. This natural benzoquinone bear a lipophilic chain and we report here the synthesis of hydrophilic analogues of embelin. To allow a large flexibility in the nature of the hydrophilic group, three amines with different length of carbon chain bearing a protected benzoquinone were prepared. The cytotoxic effects of these derivatives were evaluated on KB cell line." @default.
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- W1996683618 date "2012-06-01" @default.
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- W1996683618 title "Synthesis and biological evaluation of hydrophilic embelin derivatives" @default.
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- W1996683618 doi "https://doi.org/10.1016/j.tet.2012.04.024" @default.
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