FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996691330> ?p ?o ?g. }

• W1996691330 endingPage "1408" @default.
• W1996691330 startingPage "1402" @default.
• W1996691330 abstract "Background. The immune defect in haemodialysis (HD) patients is associated with a monocytic dysfunction, including an increased production of proinflammatory cytokines. Monocytes fall into subpopulations comprising CD14++CD16− and CD14+CD16+ cells. Circulating numbers of the latter can rapidly increase during infectious episodes and inflammation. Methods. We determined the amount of CD14+CD16+ monocytes in HD patients and characterized their fate during HD treatment. In 34 HD patients and 17 healthy controls, the distinct cell populations were determined by differential blood counts and flow cytometry. Cells from 14 HD patients were analysed at the start, 10, 30 and 120 min thereafter, and at the end of HD treatment. Results. Before HD, patients show a monocytosis with a strongly increased CD14+CD16+ subpopulation. Early during HD treatment, circulating leukocyte numbers decrease, with monocytes being most profoundly influenced. Interestingly, among them, sequestration is most pronounced in the CD14+ CD16+ subpopulation. After 30 min, ∼83±9% of CD14+CD16+ cells are removed from circulation. This sequestration does not differ between patients treated with polyamide or haemophan membranes. The sequestration is a short‐lived temporary effect and cell numbers are replenished within 120 min of treatment for the entire monocyte population. Beyond that time point, cellular activation by the dialyser membrane becomes visible. Reappearence kinetics of CD14+CD16+ monocytes is slower; however, initial numbers are reached by the end of treatment. Conclusion. Haemodiaysis leads to temporary removal of monocytes from the bloodstream followed by the reappearance of activated cells. This might contribute to the state of chronic microinflammation, which is reflected by high levels of CD14+CD16+ monocytes." @default.
• W1996691330 created "2016-06-24" @default.
• W1996691330 creator A5002750447 @default.
• W1996691330 creator A5009201025 @default.
• W1996691330 creator A5032187954 @default.
• W1996691330 creator A5050295097 @default.
• W1996691330 creator A5075961504 @default.
• W1996691330 creator A5085882046 @default.
• W1996691330 date "2001-07-01" @default.
• W1996691330 modified "2023-09-26" @default.
• W1996691330 title "Strong depletion of CD14+CD16+ monocytes during haemodialysis treatment" @default.
• W1996691330 cites W1973677588 @default.
• W1996691330 cites W1974749956 @default.
• W1996691330 cites W1984084256 @default.
• W1996691330 cites W1985292239 @default.
• W1996691330 cites W2020354584 @default.
• W1996691330 cites W2029192259 @default.
• W1996691330 cites W2037292438 @default.
• W1996691330 cites W2038112648 @default.
• W1996691330 cites W2038523160 @default.
• W1996691330 cites W2054815957 @default.
• W1996691330 cites W2058588777 @default.
• W1996691330 cites W2070093958 @default.
• W1996691330 cites W2073201077 @default.
• W1996691330 cites W2077248714 @default.
• W1996691330 cites W2084243304 @default.
• W1996691330 cites W2098962500 @default.
• W1996691330 cites W2099675490 @default.
• W1996691330 cites W2101683974 @default.
• W1996691330 cites W2112117215 @default.
• W1996691330 cites W2128661749 @default.
• W1996691330 cites W2150781890 @default.
• W1996691330 cites W2172160601 @default.
• W1996691330 cites W2183362862 @default.
• W1996691330 cites W2186699960 @default.
• W1996691330 cites W2423089793 @default.
• W1996691330 cites W4229908229 @default.
• W1996691330 cites W4237157196 @default.
• W1996691330 doi "https://doi.org/10.1093/ndt/16.7.1402" @default.
• W1996691330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11427632" @default.
• W1996691330 hasPublicationYear "2001" @default.
• W1996691330 type Work @default.
• W1996691330 sameAs 1996691330 @default.
• W1996691330 citedByCount "69" @default.
• W1996691330 countsByYear W19966913302012 @default.
• W1996691330 countsByYear W19966913302013 @default.
• W1996691330 countsByYear W19966913302014 @default.
• W1996691330 countsByYear W19966913302015 @default.
• W1996691330 countsByYear W19966913302016 @default.
• W1996691330 countsByYear W19966913302017 @default.
• W1996691330 countsByYear W19966913302018 @default.
• W1996691330 countsByYear W19966913302019 @default.
• W1996691330 countsByYear W19966913302020 @default.
• W1996691330 countsByYear W19966913302021 @default.
• W1996691330 countsByYear W19966913302022 @default.
• W1996691330 crossrefType "journal-article" @default.
• W1996691330 hasAuthorship W1996691330A5002750447 @default.
• W1996691330 hasAuthorship W1996691330A5009201025 @default.
• W1996691330 hasAuthorship W1996691330A5032187954 @default.
• W1996691330 hasAuthorship W1996691330A5050295097 @default.
• W1996691330 hasAuthorship W1996691330A5075961504 @default.
• W1996691330 hasAuthorship W1996691330A5085882046 @default.
• W1996691330 hasBestOaLocation W19966913301 @default.
• W1996691330 hasConcept C114684123 @default.
• W1996691330 hasConcept C126322002 @default.
• W1996691330 hasConcept C164027704 @default.
• W1996691330 hasConcept C167672396 @default.
• W1996691330 hasConcept C203014093 @default.
• W1996691330 hasConcept C2776914184 @default.
• W1996691330 hasConcept C2778513237 @default.
• W1996691330 hasConcept C2781184567 @default.
• W1996691330 hasConcept C2781462264 @default.
• W1996691330 hasConcept C2908647359 @default.
• W1996691330 hasConcept C553184892 @default.
• W1996691330 hasConcept C71924100 @default.
• W1996691330 hasConcept C8891405 @default.
• W1996691330 hasConcept C99454951 @default.
• W1996691330 hasConceptScore W1996691330C114684123 @default.
• W1996691330 hasConceptScore W1996691330C126322002 @default.
• W1996691330 hasConceptScore W1996691330C164027704 @default.
• W1996691330 hasConceptScore W1996691330C167672396 @default.
• W1996691330 hasConceptScore W1996691330C203014093 @default.
• W1996691330 hasConceptScore W1996691330C2776914184 @default.
• W1996691330 hasConceptScore W1996691330C2778513237 @default.
• W1996691330 hasConceptScore W1996691330C2781184567 @default.
• W1996691330 hasConceptScore W1996691330C2781462264 @default.
• W1996691330 hasConceptScore W1996691330C2908647359 @default.
• W1996691330 hasConceptScore W1996691330C553184892 @default.
• W1996691330 hasConceptScore W1996691330C71924100 @default.
• W1996691330 hasConceptScore W1996691330C8891405 @default.
• W1996691330 hasConceptScore W1996691330C99454951 @default.
• W1996691330 hasIssue "7" @default.
• W1996691330 hasLocation W19966913301 @default.
• W1996691330 hasLocation W19966913302 @default.
• W1996691330 hasOpenAccess W1996691330 @default.
• W1996691330 hasPrimaryLocation W19966913301 @default.
• W1996691330 hasRelatedWork W1584783298 @default.
• W1996691330 hasRelatedWork W1991026693 @default.

• next