FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996742451> ?p ?o ?g. }

• W1996742451 endingPage "1117" @default.
• W1996742451 startingPage "1107" @default.
• W1996742451 abstract "In order to establish a valid surrogate outcome measure, it must be shown that the outcome measure (chest HRCT scores in cystic fibrosis [CF] patients) demonstrates strong statistical association with established endpoints of disease, such as Pseudomonas aeruginosa (Pa) airway acquisition, acute exacerbations, or mortality.We estimated and tested the association between Pa infection status (Pa+ vs. Pa-) and baseline chest HRCT scores in 25 children with mild-to-moderate CF lung disease. For comparison, we estimated the association between Pa status and pulmonary function tests (PFTs), chest X-rays (CXR) scores, and BMI. Pa acquisition was determined from respiratory culture results and systematic review of clinic notes.All subjects had respiratory cultures performed prior to or at baseline with a median of 19 months of retrospective culture observation (SD = 15.7 months, range: 0-52.5 months). The difference between age-adjusted mean total HRCT score for Pa+ versus Pa- was highly significant (P < 0.00001) with a near-perfect separation between scores in Pa+ versus Pa- patients. Similar results were found for several HRCT sub-scores. Among PFTs, only residual volume-to-total lung capacity (RV/TLC) had a significant difference between group means (P = 0.03), but the overlap between groups in RV/TLC measurements was large.CF HRCT scores correlate highly with Pa acquisition, a clinically meaningful measure of progressing CF lung disease. HRCT scores are highly sensitive at predicting Pa acquisition status, while most PFT measures, chest radiograph (CXR) scores, and body mass index are not. These results provide further evidence that HRCT is appropriate for use in patient care and as an outcome measure in clinical trials." @default.
• W1996742451 created "2016-06-24" @default.
• W1996742451 creator A5001508577 @default.
• W1996742451 creator A5029245318 @default.
• W1996742451 creator A5047022770 @default.
• W1996742451 creator A5057903251 @default.
• W1996742451 creator A5072939873 @default.
• W1996742451 date "2009-10-12" @default.
• W1996742451 modified "2023-09-26" @default.
• W1996742451 title "Cystic fibrosis HRCT scores correlate strongly with pseudomonas infection" @default.
• W1996742451 cites W1971558827 @default.
• W1996742451 cites W1979104576 @default.
• W1996742451 cites W1987392485 @default.
• W1996742451 cites W1989143325 @default.
• W1996742451 cites W1989961653 @default.
• W1996742451 cites W1994869590 @default.
• W1996742451 cites W1997013992 @default.
• W1996742451 cites W1998026083 @default.
• W1996742451 cites W2000508966 @default.
• W1996742451 cites W2022694851 @default.
• W1996742451 cites W2028502510 @default.
• W1996742451 cites W2034261392 @default.
• W1996742451 cites W2035100722 @default.
• W1996742451 cites W2037789035 @default.
• W1996742451 cites W2053471558 @default.
• W1996742451 cites W2055857822 @default.
• W1996742451 cites W2060085561 @default.
• W1996742451 cites W2068148539 @default.
• W1996742451 cites W2085376909 @default.
• W1996742451 cites W2088849723 @default.
• W1996742451 cites W2096632908 @default.
• W1996742451 cites W2102850422 @default.
• W1996742451 cites W2109939030 @default.
• W1996742451 cites W2111004044 @default.
• W1996742451 cites W2111878868 @default.
• W1996742451 cites W2116795675 @default.
• W1996742451 cites W2118540215 @default.
• W1996742451 cites W2119322789 @default.
• W1996742451 cites W2124537635 @default.
• W1996742451 cites W2124747901 @default.
• W1996742451 cites W2126690774 @default.
• W1996742451 cites W2137312733 @default.
• W1996742451 cites W2142443730 @default.
• W1996742451 cites W2144102711 @default.
• W1996742451 cites W2153102800 @default.
• W1996742451 cites W2153703978 @default.
• W1996742451 cites W2155949904 @default.
• W1996742451 cites W2158898740 @default.
• W1996742451 cites W3143949042 @default.
• W1996742451 doi "https://doi.org/10.1002/ppul.21107" @default.
• W1996742451 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19824046" @default.
• W1996742451 hasPublicationYear "2009" @default.
• W1996742451 type Work @default.
• W1996742451 sameAs 1996742451 @default.
• W1996742451 citedByCount "28" @default.
• W1996742451 countsByYear W19967424512012 @default.
• W1996742451 countsByYear W19967424512013 @default.
• W1996742451 countsByYear W19967424512014 @default.
• W1996742451 countsByYear W19967424512015 @default.
• W1996742451 countsByYear W19967424512016 @default.
• W1996742451 countsByYear W19967424512017 @default.
• W1996742451 countsByYear W19967424512018 @default.
• W1996742451 countsByYear W19967424512019 @default.
• W1996742451 countsByYear W19967424512020 @default.
• W1996742451 countsByYear W19967424512021 @default.
• W1996742451 countsByYear W19967424512022 @default.
• W1996742451 crossrefType "journal-article" @default.
• W1996742451 hasAuthorship W1996742451A5001508577 @default.
• W1996742451 hasAuthorship W1996742451A5029245318 @default.
• W1996742451 hasAuthorship W1996742451A5047022770 @default.
• W1996742451 hasAuthorship W1996742451A5057903251 @default.
• W1996742451 hasAuthorship W1996742451A5072939873 @default.
• W1996742451 hasConcept C126322002 @default.
• W1996742451 hasConcept C141071460 @default.
• W1996742451 hasConcept C27101514 @default.
• W1996742451 hasConcept C2776178081 @default.
• W1996742451 hasConcept C2776938444 @default.
• W1996742451 hasConcept C2777714996 @default.
• W1996742451 hasConcept C2780221984 @default.
• W1996742451 hasConcept C2781137159 @default.
• W1996742451 hasConcept C71924100 @default.
• W1996742451 hasConcept C75603125 @default.
• W1996742451 hasConcept C90924648 @default.
• W1996742451 hasConceptScore W1996742451C126322002 @default.
• W1996742451 hasConceptScore W1996742451C141071460 @default.
• W1996742451 hasConceptScore W1996742451C27101514 @default.
• W1996742451 hasConceptScore W1996742451C2776178081 @default.
• W1996742451 hasConceptScore W1996742451C2776938444 @default.
• W1996742451 hasConceptScore W1996742451C2777714996 @default.
• W1996742451 hasConceptScore W1996742451C2780221984 @default.
• W1996742451 hasConceptScore W1996742451C2781137159 @default.
• W1996742451 hasConceptScore W1996742451C71924100 @default.
• W1996742451 hasConceptScore W1996742451C75603125 @default.
• W1996742451 hasConceptScore W1996742451C90924648 @default.
• W1996742451 hasFunder F4320306168 @default.
• W1996742451 hasFunder F4320332193 @default.
• W1996742451 hasFunder F4320337375 @default.
• W1996742451 hasIssue "11" @default.

• next