Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996765504> ?p ?o ?g. }
- W1996765504 endingPage "227" @default.
- W1996765504 startingPage "221" @default.
- W1996765504 abstract "Abstract Down syndrome (DS) is the most commonly identified genetic form of mental retardation and the leading cause of specific birth defects and medical conditions. Traditional epidemiological studies to determine the prevalence, cause, and clinical significance of the syndrome have been conducted over the last 100 years. DS has been estimated to occur in ∼1 in 732 infants in the United States, although there is some evidence that variability in prevalence of estimates exist among racial/ethnic groups. Progress has been made in characterizing the specific types of chromosome errors that lead to DS and in identifying associated factors that increase the risk of chromosome 21 malsegregation, i.e., advanced maternal age and recombination. Studies to examine the variability of the presence of specific DS‐associated birth defects and medical conditions provide evidence for genetic and environmental modifiers. Here, we provide a brief survey of studies that address the current state of the field and suggest gaps in research that can soon be filled with new multidisciplinary approaches and technological advances. © 2007 Wiley‐Liss, Inc. MRDD Research Reviews 2007;13:221–227." @default.
- W1996765504 created "2016-06-24" @default.
- W1996765504 creator A5014880493 @default.
- W1996765504 creator A5046083954 @default.
- W1996765504 creator A5046687796 @default.
- W1996765504 creator A5049260570 @default.
- W1996765504 date "2007-01-01" @default.
- W1996765504 modified "2023-10-11" @default.
- W1996765504 title "Epidemiology of Down syndrome" @default.
- W1996765504 cites W1504885390 @default.
- W1996765504 cites W1520866224 @default.
- W1996765504 cites W1934232739 @default.
- W1996765504 cites W1964067226 @default.
- W1996765504 cites W1965313517 @default.
- W1996765504 cites W1965908672 @default.
- W1996765504 cites W1975652111 @default.
- W1996765504 cites W1984310558 @default.
- W1996765504 cites W1984955075 @default.
- W1996765504 cites W1987678492 @default.
- W1996765504 cites W1987831440 @default.
- W1996765504 cites W1995893698 @default.
- W1996765504 cites W1997559493 @default.
- W1996765504 cites W2000150704 @default.
- W1996765504 cites W2001635099 @default.
- W1996765504 cites W2008131934 @default.
- W1996765504 cites W2008896773 @default.
- W1996765504 cites W2012419320 @default.
- W1996765504 cites W2014629546 @default.
- W1996765504 cites W2021647091 @default.
- W1996765504 cites W2022793225 @default.
- W1996765504 cites W2024978198 @default.
- W1996765504 cites W2025755447 @default.
- W1996765504 cites W2025782007 @default.
- W1996765504 cites W2026530864 @default.
- W1996765504 cites W2030381493 @default.
- W1996765504 cites W2031217539 @default.
- W1996765504 cites W2032018719 @default.
- W1996765504 cites W2033708398 @default.
- W1996765504 cites W2034061050 @default.
- W1996765504 cites W2040904496 @default.
- W1996765504 cites W2045204838 @default.
- W1996765504 cites W2048731329 @default.
- W1996765504 cites W2050259031 @default.
- W1996765504 cites W2059499274 @default.
- W1996765504 cites W2066594097 @default.
- W1996765504 cites W2068954502 @default.
- W1996765504 cites W2070808285 @default.
- W1996765504 cites W2071282605 @default.
- W1996765504 cites W2074493348 @default.
- W1996765504 cites W2077347324 @default.
- W1996765504 cites W2078276871 @default.
- W1996765504 cites W2083005879 @default.
- W1996765504 cites W2087074707 @default.
- W1996765504 cites W2090589400 @default.
- W1996765504 cites W2092815939 @default.
- W1996765504 cites W2096389402 @default.
- W1996765504 cites W2097367536 @default.
- W1996765504 cites W2111171125 @default.
- W1996765504 cites W2111498062 @default.
- W1996765504 cites W2111560825 @default.
- W1996765504 cites W2121274568 @default.
- W1996765504 cites W2124036673 @default.
- W1996765504 cites W2129061276 @default.
- W1996765504 cites W2134046362 @default.
- W1996765504 cites W2134198313 @default.
- W1996765504 cites W2134550036 @default.
- W1996765504 cites W2136609444 @default.
- W1996765504 cites W2148883664 @default.
- W1996765504 cites W2157338534 @default.
- W1996765504 cites W2163451726 @default.
- W1996765504 cites W2186770490 @default.
- W1996765504 cites W2290819778 @default.
- W1996765504 cites W2407644960 @default.
- W1996765504 cites W4230599058 @default.
- W1996765504 cites W4232591110 @default.
- W1996765504 cites W4246849308 @default.
- W1996765504 cites W4250058673 @default.
- W1996765504 cites W4254694901 @default.
- W1996765504 cites W4299135094 @default.
- W1996765504 cites W4361745143 @default.
- W1996765504 doi "https://doi.org/10.1002/mrdd.20157" @default.
- W1996765504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17910090" @default.
- W1996765504 hasPublicationYear "2007" @default.
- W1996765504 type Work @default.
- W1996765504 sameAs 1996765504 @default.
- W1996765504 citedByCount "390" @default.
- W1996765504 countsByYear W19967655042012 @default.
- W1996765504 countsByYear W19967655042013 @default.
- W1996765504 countsByYear W19967655042014 @default.
- W1996765504 countsByYear W19967655042015 @default.
- W1996765504 countsByYear W19967655042016 @default.
- W1996765504 countsByYear W19967655042017 @default.
- W1996765504 countsByYear W19967655042018 @default.
- W1996765504 countsByYear W19967655042019 @default.
- W1996765504 countsByYear W19967655042020 @default.
- W1996765504 countsByYear W19967655042021 @default.
- W1996765504 countsByYear W19967655042022 @default.
- W1996765504 countsByYear W19967655042023 @default.