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- W1996793927 abstract "Mice deficient in 14-3-3ε exhibit abnormal neuronal migration and die perinatally. We report here the first large-scale analysis of 14-3-3 interacting partners from primary animal tissue, identifying from embryonic murine brain 163 14-3-3ε interacting proteins and 85 phosphorylation sites on these proteins. Phosphorylation of the deubiquitinating enzyme USP8 at serine 680 was found essential for its interaction with 14-3-3ε and for maintaining USP8 in the cytosol. Keywords: phosphoproteomics • 14-3-3 • epsilon • brain development • kinase • phosphorylation • mass spectrometry • deubiquitination" @default.
- W1996793927 created "2016-06-24" @default.
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- W1996793927 date "2006-08-02" @default.
- W1996793927 modified "2023-09-23" @default.
- W1996793927 title "Identification of 14-3-3ε Substrates from Embryonic Murine Brain" @default.
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- W1996793927 doi "https://doi.org/10.1021/pr060206k" @default.
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