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- W1996804547 abstract "Indocyanine green for injection (IC-Green, Akorn Inc., Buffalo Grove, IL) is a sterile, lyophilized green powder dye containing 25 mg of drug with no more than 5% sodium iodide. The drug is used for several diagnostic purposes, including determining cardiac output and hepatic function, and for ophthalmic angiography. At our institution, it is most commonly used for intravitreal injection to enhance visualization during retinal procedures. This drug performs particularly well compared with other agents used in retinal tissue. For many months, the manufacturer’s commercial product had not been available due to restructuring of the manufacturing site. It became commercially available again in October 2007. The ongoing need for use in retinal procedures when the commercial drug was unavailable prompted ophthalmologists to search for other sources of the drug. With requests from several ophthalmologists at our hospital, we investigated the possibility of obtaining a compounded product from several specialty pharmacies. We recently implemented a hospital policy approved by the pharmacy and therapeutics committee for evaluating the compounding procedures of outside pharmacies and their sterile products. Factors addressed in our policy include adherence to United States Pharmacopeia chapter 797 guidelines on compounding sterile products, the designated grade of the chemicals used, documentation of a quality-assurance program and parameters (i.e., testing for pyrogens, viral contamination, sterility, potency, and pH), licensure, and other factors.1,2" @default.
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- W1996804547 date "2008-03-15" @default.
- W1996804547 modified "2023-09-27" @default.
- W1996804547 title "Indocyanine green availability from compounding pharmacies" @default.
- W1996804547 doi "https://doi.org/10.2146/ajhp070530" @default.
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