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• W1996809999 abstract "Background The purpose of the current study was to evaluate the accuracy of 18F-FDG PET/CT in staging hilar cholangiocarcinoma. Materials and Methods From June 2004 to December 2007, patients evaluated for surgical treatment of hilar cholangiocarcinoma were entered into a prospective database. Dual modality 18F-FDG PET/CT was performed before surgery. The report was reviewed with comparison to the operative and pathological results in each case for tumour-node-metastasis staging. Results Seventeen patients (6 women, 11 men) of a median age of 62 years were included in the study. Radical tumour resection was performed on seven patients. Ten patients underwent surgical exploration. The sensitivity of PET/CT in detecting primary tumour was found to be 58.8% (25% in T2 tumour, 70% in T3 tumour, 66.7% in T4 tumour). The sensitivity/specificity of PET/CT in detecting lymph node metastasis and distant metastasis were 41.7%/80% and 55.6%/87.5%, respectively. Positive 18F-FDG uptake in the bile duct was found to be associated with surgical non-resectability (P = 0.05). Conclusion Dual-modality PET/CT imaging was found to have a high specificity in detection of lymph node and distant metastasis in hilar cholangiocarcinoma, with a limited value in correct judgement of surgical resectability for tumours in stadium UICC I-III. J. Surg. Oncol. © 2008 Wiley-Liss, Inc." @default.
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• W1996809999 date "2008-11-01" @default.
• W1996809999 modified "2023-10-18" @default.
• W1996809999 title "Preoperative assessment of hilar cholangiocarcinoma by dual-modality PET/CT" @default.
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• W1996809999 doi "https://doi.org/10.1002/jso.21136" @default.
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