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- W1996861903 abstract "SUPPLEMENTARY ORAL ANTIDIABETICS: Thiazolidinediones or glitazones are a new class of oral antidiabetics, the effects on blood sugar control of which are mediated by the sensitivity of the peripheral tissue to the effect of insulin. Hence, their effect is complementary to that of the insulin secreting agents and that of metformin, which acts by blocking the hepatic production of glucose. OTHER BENEFICIAL EFFECTS: Other than their effect on blood glucose, thiazolidinediones have a favorable influence upon the cardiovascular risk factors or markers such as blood pressure, C-reactive protein and metalloproteinase-9. They also appear to induce long term preservation of the beta-cell capital. Principle side effects are salt-water retention with a risk of decompensation of a pre-existing heart failure and weight gain with regard to the subcutaneous adipose tissue, without deleterious effects on blood glucose control." @default.
- W1996861903 created "2016-06-24" @default.
- W1996861903 creator A5028939387 @default.
- W1996861903 date "2004-09-01" @default.
- W1996861903 modified "2023-10-01" @default.
- W1996861903 title "Place des thiazolidinediones dans le traitement du diabète de type 2" @default.
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- W1996861903 doi "https://doi.org/10.1016/s0755-4982(04)98833-1" @default.
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