FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996871192> ?p ?o ?g. }

• W1996871192 endingPage "769" @default.
• W1996871192 startingPage "769" @default.
• W1996871192 abstract "The chick retina and pineal gland exhibit circadian oscillations in biochemical and physiological processes in vivo and in vitro, which entrain to 24-hour light-dark cycles. However, the phototransduction mechanisms responsible for entrainment are largely unknown. The present study characterizes two candidate opsinlike genes that may play a role in entrainment of the clocks in these tissues.Bioinformatics, cladistic techniques, and in situ hybridization and Northern blot analyses were conducted to characterize, localize, and determine the circadian expression of the candidate opsinlike genes in the retina and pineal gland.Two candidate photosensors and/or photoisomerases were predominantly distributed within the pineal gland and retina: the retinal pigmented epithelium-derived rhodopsin homologue (peropsin, gRrh) and retinal G-protein-coupled receptor opsin (RGR opsin, gRgr). Northern blot and in situ analyses revealed mRNA expression for both opsins in the pineal gland, retina, and brain tissue. The mRNA for both genes within the pineal gland and retina is regulated on a circadian basis such that they are highest in late subjective day. Digoxigenin in situ analyses showed retinal gRgr message within the inner nuclear layer (INL) and retinal ganglion cell layer (RGL), whereas gRrh message was distributed predominantly in the RGL. In the pineal gland, gRgr message was sparsely distributed among pinealocytes in follicles, but not within the follicles themselves, whereas gRrh was localized in interstitial areas indicative of astrocytic and/or endothelial origin.The presence of two putative photoisomerases within the pineal gland and in retinal layers associated with biological clock function provides two candidate opsinlike genes that may serve in the visual cycle regulation of the circadian clock." @default.
• W1996871192 created "2016-06-24" @default.
• W1996871192 creator A5009735497 @default.
• W1996871192 creator A5042022599 @default.
• W1996871192 date "2004-03-01" @default.
• W1996871192 modified "2023-10-16" @default.
• W1996871192 title "Opsin Photoisomerases in the Chick Retina and Pineal Gland: Characterization, Localization, and Circadian Regulation" @default.
• W1996871192 cites W1493050395 @default.
• W1996871192 cites W1571589296 @default.
• W1996871192 cites W1584596151 @default.
• W1996871192 cites W175832943 @default.
• W1996871192 cites W1935419509 @default.
• W1996871192 cites W1964497315 @default.
• W1996871192 cites W1967265820 @default.
• W1996871192 cites W1970793856 @default.
• W1996871192 cites W1971063924 @default.
• W1996871192 cites W1971524741 @default.
• W1996871192 cites W1972446958 @default.
• W1996871192 cites W1974207081 @default.
• W1996871192 cites W1979385177 @default.
• W1996871192 cites W1985078116 @default.
• W1996871192 cites W1985783829 @default.
• W1996871192 cites W1987654762 @default.
• W1996871192 cites W1989189843 @default.
• W1996871192 cites W1989876250 @default.
• W1996871192 cites W1993620919 @default.
• W1996871192 cites W1998840349 @default.
• W1996871192 cites W1999522064 @default.
• W1996871192 cites W2003239512 @default.
• W1996871192 cites W2004381001 @default.
• W1996871192 cites W2007897296 @default.
• W1996871192 cites W2009493198 @default.
• W1996871192 cites W2015185845 @default.
• W1996871192 cites W2016290238 @default.
• W1996871192 cites W2019712448 @default.
• W1996871192 cites W2025126091 @default.
• W1996871192 cites W2036120795 @default.
• W1996871192 cites W2044092807 @default.
• W1996871192 cites W2047196516 @default.
• W1996871192 cites W2047508855 @default.
• W1996871192 cites W2052079679 @default.
• W1996871192 cites W2057580385 @default.
• W1996871192 cites W2059002026 @default.
• W1996871192 cites W2064707341 @default.
• W1996871192 cites W2066592246 @default.
• W1996871192 cites W2071250685 @default.
• W1996871192 cites W2071317669 @default.
• W1996871192 cites W2073585560 @default.
• W1996871192 cites W2075491849 @default.
• W1996871192 cites W2091844374 @default.
• W1996871192 cites W2105050095 @default.
• W1996871192 cites W2106882534 @default.
• W1996871192 cites W2113216985 @default.
• W1996871192 cites W2123702853 @default.
• W1996871192 cites W2133373728 @default.
• W1996871192 cites W2137464479 @default.
• W1996871192 cites W2150297520 @default.
• W1996871192 cites W2156481992 @default.
• W1996871192 cites W2158954251 @default.
• W1996871192 cites W2164698226 @default.
• W1996871192 cites W2168288068 @default.
• W1996871192 cites W2168965096 @default.
• W1996871192 cites W2274897444 @default.
• W1996871192 cites W2319191844 @default.
• W1996871192 doi "https://doi.org/10.1167/iovs.03-1125" @default.
• W1996871192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14985289" @default.
• W1996871192 hasPublicationYear "2004" @default.
• W1996871192 type Work @default.
• W1996871192 sameAs 1996871192 @default.
• W1996871192 citedByCount "44" @default.
• W1996871192 countsByYear W19968711922012 @default.
• W1996871192 countsByYear W19968711922013 @default.
• W1996871192 countsByYear W19968711922014 @default.
• W1996871192 countsByYear W19968711922015 @default.
• W1996871192 countsByYear W19968711922016 @default.
• W1996871192 countsByYear W19968711922017 @default.
• W1996871192 countsByYear W19968711922018 @default.
• W1996871192 countsByYear W19968711922019 @default.
• W1996871192 countsByYear W19968711922020 @default.
• W1996871192 countsByYear W19968711922022 @default.
• W1996871192 crossrefType "journal-article" @default.
• W1996871192 hasAuthorship W1996871192A5009735497 @default.
• W1996871192 hasAuthorship W1996871192A5042022599 @default.
• W1996871192 hasConcept C104317684 @default.
• W1996871192 hasConcept C121446783 @default.
• W1996871192 hasConcept C126322002 @default.
• W1996871192 hasConcept C131667965 @default.
• W1996871192 hasConcept C134018914 @default.
• W1996871192 hasConcept C150194340 @default.
• W1996871192 hasConcept C169760540 @default.
• W1996871192 hasConcept C202023056 @default.
• W1996871192 hasConcept C202033177 @default.
• W1996871192 hasConcept C2777093970 @default.
• W1996871192 hasConcept C2778024200 @default.
• W1996871192 hasConcept C2780059843 @default.
• W1996871192 hasConcept C2780188069 @default.
• W1996871192 hasConcept C2780827179 @default.
• W1996871192 hasConcept C30028475 @default.

• next