FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996877300> ?p ?o ?g. }

• W1996877300 endingPage "35" @default.
• W1996877300 startingPage "30" @default.
• W1996877300 abstract "We performed a randomized, double-masked, parallel-groups, placebo-controlled trial of recombinant granulocyte colony-stimulating factor (rG-CSF) administration to 44 preterm neonates who had blood cultures obtained and antibiotics begun because of the clinical diagnosis of early-onset sepsis. Two primary outcome variables were tested 1) mortality and 2) development of nosocomial infections over the 2-week period after dosing.The treatment group (n = 22) received 10 microgram/kg/day of intravenous rG-CSF once daily for 3 days and the placebo group (n = 22) received the same volume of a visually indistinguishable vehicle. Mortality and culture-proven nosocomial infections were recorded. Immediately before the first, second, and third doses, and again 10 days after the first dose, serum concentrations were determined for tumor necrosis factor-alpha, interleukin 6, granulocyte-macrophage colony stimulating factor, and G-CSF, and blood leukocyte counts, absolute neutrophil counts, immature/total neutrophil ratios, platelet counts, and hemoglobin concentrations were measured.The treatment and placebo groups were of similar gestational age (29 +/- 3 vs 31 +/- 3 weeks) and birth weight (1376 +/- 491 vs 1404 +/- 508 g), and had similar Apgar scores and 24-hour Score for Neonatal Acute Physiology scores. The mortality rate was not different between treatment and placebo groups. However, the occurrence of a subsequent nosocomial infection was lower in the rG-CSF recipients (relative risk:.19; 95% confidence interval:.05-.78). rG-CSF treatment did not alter the serum concentrations of the cytokines measured (except for G-CSF). Serum G-CSF levels and blood neutrophil counts were higher in the treatment than in the placebo group 24 hours and 48 hours after dosing.Administration of 3 daily doses of rG-CSF (10 microgram/kg/day) to premature neonates with the clinical diagnosis of early-onset sepsis did not improve mortality but was associated with acquiring fewer nosocomial infections over the subsequent 2 weeks." @default.
• W1996877300 created "2016-06-24" @default.
• W1996877300 creator A5009897933 @default.
• W1996877300 creator A5026854749 @default.
• W1996877300 creator A5028589530 @default.
• W1996877300 creator A5032926124 @default.
• W1996877300 creator A5037675336 @default.
• W1996877300 creator A5072823260 @default.
• W1996877300 creator A5087709729 @default.
• W1996877300 date "2001-01-01" @default.
• W1996877300 modified "2023-09-23" @default.
• W1996877300 title "A Randomized, Double-Masked, Placebo-Controlled Trial of Recombinant Granulocyte Colony-Stimulating Factor Administration to Preterm Infants With the Clinical Diagnosis of Early-Onset Sepsis" @default.
• W1996877300 cites W108730749 @default.
• W1996877300 cites W1493951076 @default.
• W1996877300 cites W1555387300 @default.
• W1996877300 cites W1564665732 @default.
• W1996877300 cites W1981186878 @default.
• W1996877300 cites W1984989435 @default.
• W1996877300 cites W1989449912 @default.
• W1996877300 cites W1995492727 @default.
• W1996877300 cites W1996336860 @default.
• W1996877300 cites W1999448989 @default.
• W1996877300 cites W2014251299 @default.
• W1996877300 cites W2025055728 @default.
• W1996877300 cites W2034215167 @default.
• W1996877300 cites W2042731498 @default.
• W1996877300 cites W2054008338 @default.
• W1996877300 cites W2061519078 @default.
• W1996877300 cites W2063362767 @default.
• W1996877300 cites W2077846569 @default.
• W1996877300 cites W2086497336 @default.
• W1996877300 cites W2086719170 @default.
• W1996877300 cites W2122555521 @default.
• W1996877300 cites W2314427160 @default.
• W1996877300 cites W2408483919 @default.
• W1996877300 cites W2430427671 @default.
• W1996877300 cites W274435141 @default.
• W1996877300 cites W4249065032 @default.
• W1996877300 cites W75705058 @default.
• W1996877300 doi "https://doi.org/10.1542/peds.107.1.30" @default.
• W1996877300 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11134430" @default.
• W1996877300 hasPublicationYear "2001" @default.
• W1996877300 type Work @default.
• W1996877300 sameAs 1996877300 @default.
• W1996877300 citedByCount "85" @default.
• W1996877300 countsByYear W19968773002012 @default.
• W1996877300 countsByYear W19968773002013 @default.
• W1996877300 countsByYear W19968773002014 @default.
• W1996877300 countsByYear W19968773002016 @default.
• W1996877300 countsByYear W19968773002017 @default.
• W1996877300 countsByYear W19968773002018 @default.
• W1996877300 countsByYear W19968773002019 @default.
• W1996877300 countsByYear W19968773002020 @default.
• W1996877300 countsByYear W19968773002021 @default.
• W1996877300 countsByYear W19968773002022 @default.
• W1996877300 countsByYear W19968773002023 @default.
• W1996877300 crossrefType "journal-article" @default.
• W1996877300 hasAuthorship W1996877300A5009897933 @default.
• W1996877300 hasAuthorship W1996877300A5026854749 @default.
• W1996877300 hasAuthorship W1996877300A5028589530 @default.
• W1996877300 hasAuthorship W1996877300A5032926124 @default.
• W1996877300 hasAuthorship W1996877300A5037675336 @default.
• W1996877300 hasAuthorship W1996877300A5072823260 @default.
• W1996877300 hasAuthorship W1996877300A5087709729 @default.
• W1996877300 hasConcept C126322002 @default.
• W1996877300 hasConcept C142724271 @default.
• W1996877300 hasConcept C168563851 @default.
• W1996877300 hasConcept C203014093 @default.
• W1996877300 hasConcept C204787440 @default.
• W1996877300 hasConcept C27081682 @default.
• W1996877300 hasConcept C2775953899 @default.
• W1996877300 hasConcept C2776694085 @default.
• W1996877300 hasConcept C2777063308 @default.
• W1996877300 hasConcept C2777767877 @default.
• W1996877300 hasConcept C2778376644 @default.
• W1996877300 hasConcept C2778384902 @default.
• W1996877300 hasConcept C2778488018 @default.
• W1996877300 hasConcept C2779234561 @default.
• W1996877300 hasConcept C29730261 @default.
• W1996877300 hasConcept C54355233 @default.
• W1996877300 hasConcept C71924100 @default.
• W1996877300 hasConcept C74133956 @default.
• W1996877300 hasConcept C86803240 @default.
• W1996877300 hasConcept C90924648 @default.
• W1996877300 hasConceptScore W1996877300C126322002 @default.
• W1996877300 hasConceptScore W1996877300C142724271 @default.
• W1996877300 hasConceptScore W1996877300C168563851 @default.
• W1996877300 hasConceptScore W1996877300C203014093 @default.
• W1996877300 hasConceptScore W1996877300C204787440 @default.
• W1996877300 hasConceptScore W1996877300C27081682 @default.
• W1996877300 hasConceptScore W1996877300C2775953899 @default.
• W1996877300 hasConceptScore W1996877300C2776694085 @default.
• W1996877300 hasConceptScore W1996877300C2777063308 @default.
• W1996877300 hasConceptScore W1996877300C2777767877 @default.
• W1996877300 hasConceptScore W1996877300C2778376644 @default.
• W1996877300 hasConceptScore W1996877300C2778384902 @default.
• W1996877300 hasConceptScore W1996877300C2778488018 @default.
• W1996877300 hasConceptScore W1996877300C2779234561 @default.

• next