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- W1996891710 abstract "Smoking causes oral fibrosis. In a recent report, Takeuchi and colleagues (J Dent Res 89:34-9, 2010) evaluate whether nicotine can directly elevate collagen production in gingival fibroblasts. They show that CCN2 (connective tissue growth factor, CTGF) is elevated in response to nicotine and that a neutralizing CCN2 antibody reduces the ability of nicotine to promote collagen production. These data suggest that nicotine from smoking may promote periodontal fibrosis via CCN2. This commentary summarizes these findings." @default.
- W1996891710 created "2016-06-24" @default.
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- W1996891710 date "2010-08-17" @default.
- W1996891710 modified "2023-09-27" @default.
- W1996891710 title "When there’s smoke there’s.....CCN2" @default.
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- W1996891710 doi "https://doi.org/10.1007/s12079-010-0096-9" @default.
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