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• W1996914521 abstract "Three novel scalarane sesterterpenes were isolated from a Korean marine sponge, Psammocinia sp., along with four known derivatives. Their structures were elucidated on the basis of NMR, MS and IR spectroscopic data. The three new compounds are 12-deacetoxy-23-hydroxyscalaradial (1), 12-dehydroxy-23-hydroxyhyrtiolide (2) and 12-O-acetyl-16-deacetoxy-23-acetoxyscalarafuran (3), respectively, and the four known compounds are 12-deacetoxy-23-hydroxyheteronemin (4), 12-deacetoxy-23-acetoxy-19-O-acetylscalarin (5), 12-deacetoxy-23-O-acetoxyheteronemin (6) and 12-deacetoxyscalaradial (7). They exhibited cytotoxicity against intractable human cancer cell lines A498, ACHN, MIA-paca and PANC-1, with an IC50 range of 0.4-48 μM." @default.
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• W1996914521 date "2013-04-01" @default.
• W1996914521 modified "2023-10-14" @default.
• W1996914521 title "Cytotoxic scalarane sesterterpenes from a Korean marine sponge Psammocinia sp." @default.
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• W1996914521 doi "https://doi.org/10.1016/j.bmcl.2013.02.061" @default.
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