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- W1996930587 abstract "Long-term exposure of sexually mature female rhesus monkeys (Macaca mulata) to thrice weekly injections of Δ9-tetrahydrocannabinol resulted in a disruption of menstrual cycles that lasted for several months. This period was marked by an absence of ovulation and decreased basal concentrations of gonadotropin and sex steroids in the plasma. After this period, normal cycles and hormone concentrations were reestablished. These studies demonstrate that in rhesus monkeys subjected to long-term treatment with Δ9-tetrahydrocannabinol tolerance develops to the disruptive effects of the drug on the menstrual cycle." @default.
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- W1996930587 date "1983-03-25" @default.
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- W1996930587 title "Tolerance Develops to the Disruptive Effects of Δ <sup>9</sup> -Tetrahydrocannabinol on Primate Menstrual Cycle" @default.
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- W1996930587 doi "https://doi.org/10.1126/science.6298938" @default.
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