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- W1996936899 abstract "Monogamously-mated female albino mice were injected with 0·02–0·50 μg of oestradiol benzoate twice weekly for from 1 to 4 months, and then rested until 6 months had elapsed from the start of the test. All were then injected with 0·20 μg of oestradiol benzoate twice weekly for 2 months. Various control groups were also maintained. The test was then continued for a total period of 12 months, and the fertility of all groups recorded throughout. During the first injection period, a dose of 0·10 μg or less did not affect fertility. A dose of 0·50 μg delayed the first appearance of litters by approximately 1 month from the cessation of injections. During the second injection period, the uniform dose of 0·20 μg also caused a delay in the first appearance of a litter by from 10 to 49 days after stopping injections in different groups, but no correlation was found between the magnitude of this delay and previous treatment. Although litter sizes were somewhat reduced after treatment, fertility seemed otherwise to have been completely regained after each course of injections, and there were no significant histological findings in the reproductive organs at the end of the test period." @default.
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- W1996936899 date "1953-04-01" @default.
- W1996936899 modified "2023-10-05" @default.
- W1996936899 title "FURTHER STUDIES ON THE STERILIZATION OF FEMALE ALBINO MICE WITH OESTROGEN" @default.
- W1996936899 doi "https://doi.org/10.1677/joe.0.0090204" @default.
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