Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996966106> ?p ?o ?g. }
- W1996966106 endingPage "259" @default.
- W1996966106 startingPage "252" @default.
- W1996966106 abstract "The effects of cadmium exposure on serine phosphorylation of signal transducers and activators of transcription (Stats) and an upstream kinase were examined in renal proximal tubular cells. In porcine LLC-PK1 cells treated with cadmium, Stat1 and Stat3 proteins were phosphorylated at Ser727 without changing total Stat protein levels. While phosphorylated forms of the members of mitogen-activated protein kinases (MAPKs) increased in response to cadmium exposure, treatment with a p38 inhibitor, SB203580 reduced Ser727 phosphorylation of Stat1 and Stat3 markedly in LLC-PK1 cells. The expression of human matrix metalloproteinase-3 (MMP-3), a Stats-inducible gene, was found to be up-regulated in human HK-2 cells exposed to cadmium, and suppressed by preincubation with SB203580. These results suggest that cadmium might induce the phosphorylation of Stat1 and Stat3 at Ser727 via the p38 pathway at least in part, and modulate gene expression in these proximal tubular cells." @default.
- W1996966106 created "2016-06-24" @default.
- W1996966106 creator A5004181551 @default.
- W1996966106 creator A5042838191 @default.
- W1996966106 creator A5049846578 @default.
- W1996966106 creator A5080075409 @default.
- W1996966106 date "2007-11-01" @default.
- W1996966106 modified "2023-09-27" @default.
- W1996966106 title "Phosphorylation of Stats at Ser727 in renal proximal tubular epithelial cells exposed to cadmium" @default.
- W1996966106 cites W1660988713 @default.
- W1996966106 cites W1821858011 @default.
- W1996966106 cites W1899552864 @default.
- W1996966106 cites W1965119593 @default.
- W1996966106 cites W1969218281 @default.
- W1996966106 cites W1969745650 @default.
- W1996966106 cites W1971819575 @default.
- W1996966106 cites W1979785616 @default.
- W1996966106 cites W198362610 @default.
- W1996966106 cites W1988838635 @default.
- W1996966106 cites W1989829992 @default.
- W1996966106 cites W1992286324 @default.
- W1996966106 cites W1993034428 @default.
- W1996966106 cites W1996405087 @default.
- W1996966106 cites W2020281341 @default.
- W1996966106 cites W2030549445 @default.
- W1996966106 cites W2030865745 @default.
- W1996966106 cites W2031552251 @default.
- W1996966106 cites W2031890209 @default.
- W1996966106 cites W2033808806 @default.
- W1996966106 cites W2044335855 @default.
- W1996966106 cites W2046278910 @default.
- W1996966106 cites W2046848856 @default.
- W1996966106 cites W2047263793 @default.
- W1996966106 cites W2050786959 @default.
- W1996966106 cites W2065349428 @default.
- W1996966106 cites W2068502127 @default.
- W1996966106 cites W2076019855 @default.
- W1996966106 cites W2079830570 @default.
- W1996966106 cites W2083802827 @default.
- W1996966106 cites W2087527164 @default.
- W1996966106 cites W2093953283 @default.
- W1996966106 cites W2095021739 @default.
- W1996966106 cites W2114464348 @default.
- W1996966106 cites W2118090969 @default.
- W1996966106 cites W2120643436 @default.
- W1996966106 cites W2122887431 @default.
- W1996966106 cites W2124159333 @default.
- W1996966106 cites W2135124706 @default.
- W1996966106 cites W2137263316 @default.
- W1996966106 cites W2148191159 @default.
- W1996966106 cites W2169716034 @default.
- W1996966106 cites W2405787708 @default.
- W1996966106 doi "https://doi.org/10.1016/j.etap.2007.06.002" @default.
- W1996966106 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21783819" @default.
- W1996966106 hasPublicationYear "2007" @default.
- W1996966106 type Work @default.
- W1996966106 sameAs 1996966106 @default.
- W1996966106 citedByCount "10" @default.
- W1996966106 countsByYear W19969661062013 @default.
- W1996966106 countsByYear W19969661062014 @default.
- W1996966106 countsByYear W19969661062015 @default.
- W1996966106 countsByYear W19969661062020 @default.
- W1996966106 countsByYear W19969661062021 @default.
- W1996966106 crossrefType "journal-article" @default.
- W1996966106 hasAuthorship W1996966106A5004181551 @default.
- W1996966106 hasAuthorship W1996966106A5042838191 @default.
- W1996966106 hasAuthorship W1996966106A5049846578 @default.
- W1996966106 hasAuthorship W1996966106A5080075409 @default.
- W1996966106 hasConcept C11960822 @default.
- W1996966106 hasConcept C153911025 @default.
- W1996966106 hasConcept C178790620 @default.
- W1996966106 hasConcept C184235292 @default.
- W1996966106 hasConcept C185592680 @default.
- W1996966106 hasConcept C2777003663 @default.
- W1996966106 hasConcept C2778923194 @default.
- W1996966106 hasConcept C51551487 @default.
- W1996966106 hasConcept C544657597 @default.
- W1996966106 hasConcept C86803240 @default.
- W1996966106 hasConcept C95444343 @default.
- W1996966106 hasConcept C97029542 @default.
- W1996966106 hasConceptScore W1996966106C11960822 @default.
- W1996966106 hasConceptScore W1996966106C153911025 @default.
- W1996966106 hasConceptScore W1996966106C178790620 @default.
- W1996966106 hasConceptScore W1996966106C184235292 @default.
- W1996966106 hasConceptScore W1996966106C185592680 @default.
- W1996966106 hasConceptScore W1996966106C2777003663 @default.
- W1996966106 hasConceptScore W1996966106C2778923194 @default.
- W1996966106 hasConceptScore W1996966106C51551487 @default.
- W1996966106 hasConceptScore W1996966106C544657597 @default.
- W1996966106 hasConceptScore W1996966106C86803240 @default.
- W1996966106 hasConceptScore W1996966106C95444343 @default.
- W1996966106 hasConceptScore W1996966106C97029542 @default.
- W1996966106 hasIssue "3" @default.
- W1996966106 hasLocation W19969661061 @default.
- W1996966106 hasLocation W19969661062 @default.
- W1996966106 hasOpenAccess W1996966106 @default.
- W1996966106 hasPrimaryLocation W19969661061 @default.
- W1996966106 hasRelatedWork W1692925935 @default.