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- W1996985363 abstract "Standard therapy for abdominal compartment syndrome is laparotomy. In many patients, laparotomy involves a recent incision; for others, volume of resuscitation may be the cause. The components separation technique allows difficult abdominal closure. The authors studied the effect of a modified separation of parts on abdominal compartment syndrome in an animal model. Eight pigs were instrumented for measurement of central venous pressure, mean arterial pressure, peak airway pressure, and intraabdominal pressure. Intraabdominal hypertension to 25 mmHg was established with intraperitoneal fluid infusion. Modified separation of parts was performed by sequential release of the abdominal wall layers. With increased intraabdominal pressure, mean arterial pressure (55.3 ± 12.0 to 65.3 ± 11.0), central venous pressure (7.7 ± 2.4 to 13.3 ± 6.9), and peak airway pressure (20.2 ± 2.4 to 25.3 ± 4.1; p < 0.05) also increased. Maximum intraabdominal pressure was 26.0 ± 1.2 mmHg. Skin incision resulted in a decrease in intraabdominal pressure to 21.7 ± 4.5, external oblique release to 18.3 ± 3.9, internal oblique release to 13.2 ± 4.0, and transversus muscle incision to 7.0 ± 2.5 mmHg (p < 0.05). With completion of components separation, mean arterial pressure remained increased (63.2 ± 16.9), central venous pressure decreased (6.8 ± 3.6; p < 0.05), and peak airway pressure decreased (22.7 ± 3.9; p < 0.05). Modified separation of parts technique effectively releases intraabdominal hypertension and reverses the physiologic derangements associated with abdominal compartment syndrome in the animal model." @default.
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- W1996985363 date "2004-12-01" @default.
- W1996985363 modified "2023-10-15" @default.
- W1996985363 title "Modified Separation of Parts as an Intervention for Intraabdominal Hypertension and the Abdominal Compartment Syndrome in a Swine Model" @default.
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- W1996985363 doi "https://doi.org/10.1097/01.prs.0000143581.16449.39" @default.
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