FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1996997652> ?p ?o ?g. }

• W1996997652 endingPage "39" @default.
• W1996997652 startingPage "35" @default.
• W1996997652 abstract "Phenylethylidenehydrazine (PEH), a proposed metabolite of phenelzine (PLZ), was synthesized in our laboratories and administered to rats in a series of time- and dose–response studies. Phenelzine is a monoamine oxidase (MAO) inhibiting antidepressant/antipanic drug that also causes marked elevations of brain levels of the inhibitory neurotransmitter (γ-aminobutyric acid (GABA). Like PLZ, PEH inhibited GABA transaminase (GABA-T) and caused marked, long-lasting increases in rat brain levels of GABA. The addition of the double bond in PEH caused a marked decrease in its ability to inhibit MAO compared to PLZ. Given the ability of PEH to elevate GABA levels and its lack of significant effect on MAO, it may be a very effective and safe tool with which to study the role of GABA in anxiety disorders and may be a potentially useful compound to test against seizures, ischemia, mania, and stroke. Drug Dev. Res. 54:35–39, 2001. © 2001 Wiley-Liss, Inc." @default.
• W1996997652 created "2016-06-24" @default.
• W1996997652 creator A5009462512 @default.
• W1996997652 creator A5019752053 @default.
• W1996997652 creator A5040680999 @default.
• W1996997652 creator A5088403251 @default.
• W1996997652 creator A5090753984 @default.
• W1996997652 date "2001-01-01" @default.
• W1996997652 modified "2023-10-16" @default.
• W1996997652 title "?-phenylethylidenehydrazine, a novel inhibitor of GABA transaminase" @default.
• W1996997652 cites W143093875 @default.
• W1996997652 cites W1513129282 @default.
• W1996997652 cites W1546296744 @default.
• W1996997652 cites W1965232246 @default.
• W1996997652 cites W1972737444 @default.
• W1996997652 cites W1977461201 @default.
• W1996997652 cites W1983068389 @default.
• W1996997652 cites W1988340492 @default.
• W1996997652 cites W1989721331 @default.
• W1996997652 cites W1992625511 @default.
• W1996997652 cites W2018312418 @default.
• W1996997652 cites W2019602157 @default.
• W1996997652 cites W2032998637 @default.
• W1996997652 cites W2039282286 @default.
• W1996997652 cites W2043176327 @default.
• W1996997652 cites W2045307782 @default.
• W1996997652 cites W2051078728 @default.
• W1996997652 cites W2071513524 @default.
• W1996997652 cites W2075963732 @default.
• W1996997652 cites W2077775958 @default.
• W1996997652 cites W2081961205 @default.
• W1996997652 cites W2089678141 @default.
• W1996997652 cites W2090848884 @default.
• W1996997652 cites W2091839957 @default.
• W1996997652 cites W2332027120 @default.
• W1996997652 cites W4235477874 @default.
• W1996997652 doi "https://doi.org/10.1002/ddr.1202" @default.
• W1996997652 hasPublicationYear "2001" @default.
• W1996997652 type Work @default.
• W1996997652 sameAs 1996997652 @default.
• W1996997652 citedByCount "25" @default.
• W1996997652 countsByYear W19969976522012 @default.
• W1996997652 countsByYear W19969976522013 @default.
• W1996997652 countsByYear W19969976522014 @default.
• W1996997652 countsByYear W19969976522015 @default.
• W1996997652 countsByYear W19969976522018 @default.
• W1996997652 countsByYear W19969976522019 @default.
• W1996997652 countsByYear W19969976522020 @default.
• W1996997652 countsByYear W19969976522021 @default.
• W1996997652 countsByYear W19969976522022 @default.
• W1996997652 crossrefType "journal-article" @default.
• W1996997652 hasAuthorship W1996997652A5009462512 @default.
• W1996997652 hasAuthorship W1996997652A5019752053 @default.
• W1996997652 hasAuthorship W1996997652A5040680999 @default.
• W1996997652 hasAuthorship W1996997652A5088403251 @default.
• W1996997652 hasAuthorship W1996997652A5090753984 @default.
• W1996997652 hasConcept C126322002 @default.
• W1996997652 hasConcept C134018914 @default.
• W1996997652 hasConcept C170493617 @default.
• W1996997652 hasConcept C181199279 @default.
• W1996997652 hasConcept C185592680 @default.
• W1996997652 hasConcept C2776024655 @default.
• W1996997652 hasConcept C2776219046 @default.
• W1996997652 hasConcept C2777421860 @default.
• W1996997652 hasConcept C2777477808 @default.
• W1996997652 hasConcept C2777771985 @default.
• W1996997652 hasConcept C2779177272 @default.
• W1996997652 hasConcept C2781073023 @default.
• W1996997652 hasConcept C2781161787 @default.
• W1996997652 hasConcept C2910293678 @default.
• W1996997652 hasConcept C55493867 @default.
• W1996997652 hasConcept C71924100 @default.
• W1996997652 hasConcept C9497952 @default.
• W1996997652 hasConcept C98274493 @default.
• W1996997652 hasConceptScore W1996997652C126322002 @default.
• W1996997652 hasConceptScore W1996997652C134018914 @default.
• W1996997652 hasConceptScore W1996997652C170493617 @default.
• W1996997652 hasConceptScore W1996997652C181199279 @default.
• W1996997652 hasConceptScore W1996997652C185592680 @default.
• W1996997652 hasConceptScore W1996997652C2776024655 @default.
• W1996997652 hasConceptScore W1996997652C2776219046 @default.
• W1996997652 hasConceptScore W1996997652C2777421860 @default.
• W1996997652 hasConceptScore W1996997652C2777477808 @default.
• W1996997652 hasConceptScore W1996997652C2777771985 @default.
• W1996997652 hasConceptScore W1996997652C2779177272 @default.
• W1996997652 hasConceptScore W1996997652C2781073023 @default.
• W1996997652 hasConceptScore W1996997652C2781161787 @default.
• W1996997652 hasConceptScore W1996997652C2910293678 @default.
• W1996997652 hasConceptScore W1996997652C55493867 @default.
• W1996997652 hasConceptScore W1996997652C71924100 @default.
• W1996997652 hasConceptScore W1996997652C9497952 @default.
• W1996997652 hasConceptScore W1996997652C98274493 @default.
• W1996997652 hasIssue "1" @default.
• W1996997652 hasLocation W19969976521 @default.
• W1996997652 hasOpenAccess W1996997652 @default.
• W1996997652 hasPrimaryLocation W19969976521 @default.
• W1996997652 hasRelatedWork W1976377101 @default.
• W1996997652 hasRelatedWork W2001237964 @default.

• next