FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997013705> ?p ?o ?g. }

• W1997013705 endingPage "601" @default.
• W1997013705 startingPage "595" @default.
• W1997013705 abstract "Introduction The mortality rate associated with UGI bleeding remains high at 7–14%. Pharmacologic and endoscopic interventions are the current standard treatment, but there are few alternative options should these fail. This study aimed to assess the efficacy and safety of recombinant activated factor VII (rFVIIa) in the rescue treatment of severe upper gastrointestinal (UGI) bleeding. Method Eleven patients (age: 8–64 years) were treated with rFVIIa at 15.0–90 μg/kg to control UGI bleeds. All three pediatric/adolescent cases and four of the eight adults had UGI hemorrhage associated with liver disease; the origins of the bleeds for remaining adults were trauma (n=1), peptic duodenal ulcer (n=1), hemorrhagic gastritis with sepsis (n=1) and pancreatitis (n=1). Results Bleeding stopped in seven patients and was markedly reduced in two patients, while there was no change in two patients. Coagulation parameters displayed a tendency to improve, and transfusion requirements were reduced in most patients. In total, five patients died within 2 weeks of rFVIIa treatment. In each case, fatality was judged unrelated to rFVIIa treatment. No thromboembolic events occurred. Conclusions These results suggest that, even if our data are optimistic, the use of rFVIIa in the treatment of severe UGI bleeding warrants further investigation in prospective, randomized trials." @default.
• W1997013705 created "2016-06-24" @default.
• W1997013705 creator A5008438810 @default.
• W1997013705 creator A5014905187 @default.
• W1997013705 creator A5028328396 @default.
• W1997013705 creator A5032501277 @default.
• W1997013705 creator A5042584507 @default.
• W1997013705 creator A5053211205 @default.
• W1997013705 creator A5055586013 @default.
• W1997013705 creator A5056562539 @default.
• W1997013705 creator A5074117216 @default.
• W1997013705 date "2006-01-01" @default.
• W1997013705 modified "2023-09-24" @default.
• W1997013705 title "Recombinant activated factor VII in an unselected series of cases with upper gastrointestinal bleeding" @default.
• W1997013705 cites W1971158225 @default.
• W1997013705 cites W1986547366 @default.
• W1997013705 cites W1987114459 @default.
• W1997013705 cites W1993430353 @default.
• W1997013705 cites W1995491984 @default.
• W1997013705 cites W1995778698 @default.
• W1997013705 cites W1996136719 @default.
• W1997013705 cites W1998226004 @default.
• W1997013705 cites W2001222402 @default.
• W1997013705 cites W2006374009 @default.
• W1997013705 cites W2012977460 @default.
• W1997013705 cites W2014312811 @default.
• W1997013705 cites W2032637315 @default.
• W1997013705 cites W2033199355 @default.
• W1997013705 cites W2035497887 @default.
• W1997013705 cites W2040646196 @default.
• W1997013705 cites W2046936517 @default.
• W1997013705 cites W2050157196 @default.
• W1997013705 cites W2069798347 @default.
• W1997013705 cites W2073375990 @default.
• W1997013705 cites W2077001274 @default.
• W1997013705 cites W2077936287 @default.
• W1997013705 cites W2083719775 @default.
• W1997013705 cites W2084258996 @default.
• W1997013705 cites W2089587835 @default.
• W1997013705 cites W2092018547 @default.
• W1997013705 cites W2126673014 @default.
• W1997013705 cites W2132954338 @default.
• W1997013705 cites W2145791480 @default.
• W1997013705 cites W2156839378 @default.
• W1997013705 cites W2158656134 @default.
• W1997013705 cites W2285748162 @default.
• W1997013705 cites W2419519365 @default.
• W1997013705 cites W2431517904 @default.
• W1997013705 doi "https://doi.org/10.1016/j.thromres.2005.10.008" @default.
• W1997013705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16325890" @default.
• W1997013705 hasPublicationYear "2006" @default.
• W1997013705 type Work @default.
• W1997013705 sameAs 1997013705 @default.
• W1997013705 citedByCount "17" @default.
• W1997013705 countsByYear W19970137052012 @default.
• W1997013705 countsByYear W19970137052014 @default.
• W1997013705 countsByYear W19970137052015 @default.
• W1997013705 crossrefType "journal-article" @default.
• W1997013705 hasAuthorship W1997013705A5008438810 @default.
• W1997013705 hasAuthorship W1997013705A5014905187 @default.
• W1997013705 hasAuthorship W1997013705A5028328396 @default.
• W1997013705 hasAuthorship W1997013705A5032501277 @default.
• W1997013705 hasAuthorship W1997013705A5042584507 @default.
• W1997013705 hasAuthorship W1997013705A5053211205 @default.
• W1997013705 hasAuthorship W1997013705A5055586013 @default.
• W1997013705 hasAuthorship W1997013705A5056562539 @default.
• W1997013705 hasAuthorship W1997013705A5074117216 @default.
• W1997013705 hasConcept C107130276 @default.
• W1997013705 hasConcept C126322002 @default.
• W1997013705 hasConcept C141071460 @default.
• W1997013705 hasConcept C187316915 @default.
• W1997013705 hasConcept C2775967933 @default.
• W1997013705 hasConcept C2776259030 @default.
• W1997013705 hasConcept C2776345487 @default.
• W1997013705 hasConcept C2778080469 @default.
• W1997013705 hasConcept C2778384902 @default.
• W1997013705 hasConcept C2778451229 @default.
• W1997013705 hasConcept C2778961111 @default.
• W1997013705 hasConcept C71924100 @default.
• W1997013705 hasConceptScore W1997013705C107130276 @default.
• W1997013705 hasConceptScore W1997013705C126322002 @default.
• W1997013705 hasConceptScore W1997013705C141071460 @default.
• W1997013705 hasConceptScore W1997013705C187316915 @default.
• W1997013705 hasConceptScore W1997013705C2775967933 @default.
• W1997013705 hasConceptScore W1997013705C2776259030 @default.
• W1997013705 hasConceptScore W1997013705C2776345487 @default.
• W1997013705 hasConceptScore W1997013705C2778080469 @default.
• W1997013705 hasConceptScore W1997013705C2778384902 @default.
• W1997013705 hasConceptScore W1997013705C2778451229 @default.
• W1997013705 hasConceptScore W1997013705C2778961111 @default.
• W1997013705 hasConceptScore W1997013705C71924100 @default.
• W1997013705 hasIssue "5" @default.
• W1997013705 hasLocation W19970137051 @default.
• W1997013705 hasLocation W19970137052 @default.
• W1997013705 hasOpenAccess W1997013705 @default.
• W1997013705 hasPrimaryLocation W19970137051 @default.
• W1997013705 hasRelatedWork W1997013705 @default.
• W1997013705 hasRelatedWork W2008878688 @default.

• next