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- W1997041796 abstract "In the absence of a structure for a hormone-receptor complex, one may ask what systems of known structure are most likely to provide information about hormone interactions. Here, I discussed enzyme-substrate, enzyme-(protein) inhibitor, enzyme fragment (S peptide), and antibody-hapten (or antigen) interactions as possible models. Following a study of a fairly inflexible hormone (insulin) and of a flexible hormone (glucagon), I commented on probable binding regions. Finally, my conclusion was that, at present, allosteric enzymes have many of the characteristics thought to be present in those hormone-receptor interactions which activate enzymes. This model does not necessarily apply in detail to examples of hormone interactions that affect permeability of the cell wall or activate genetic processes." @default.
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- W1997041796 date "1981-05-01" @default.
- W1997041796 modified "2023-10-14" @default.
- W1997041796 title "A SURVEY OF X-RAY DIFFRACTION STUDIES OF ENZYME-OTHER MOLECULE INTERACTIONS AS POSSIBLE MODELS FOR RECEPTOR SITES" @default.
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- W1997041796 doi "https://doi.org/10.1111/j.1749-6632.1981.tb50576.x" @default.
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