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• W1997052564 abstract "In marine mollusks, many physiologic functions are regulated seasonally depending on such factors as the reproductive cycle or the presence of food. The synthesis of nitric oxide by hemocytes of Mytilus galloprovincialis is among the multiple physiologic actions in the immune response, and it is also affected by season. The maximal basal production of NO by hemocytes of M. galloprovincialis was detected in summer, whereas the minimum values were detected in winter. In winter, the presence of IL-2 induced an increase in NO production that was not detected in summer.Three months after the Prestige oil spill (November 2002), basal NO production by the hemocytes of mussels in the Galician coast showed a progressive decrease and stopping, both in summer and in winter. The characteristic increase of NO synthesis induced by IL-2 in winter also disappeared all through 2003 and 2004. The two different nitric oxide synthases previously identified by immunoblotting between 1999 and 2002 were undetectable in both 2003 and 2004.When comparing the data obtained during 2003 and 2004 to those obtained in previous years, an increase in the proportion of SH cells was detected. Also, these cells showed a higher sensitivity to apoptosis- and necrosis-inducing agents than in earlier years." @default.
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• W1997052564 date "1991-01-01" @default.
• W1997052564 modified "2023-09-27" @default.
• W1997052564 title "Similarities of signal systems in vertebrates and invertebrates: Detection, action, and interactions of immunoreactive monokines in the mussel, Mytilus edulis" @default.
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• W1997052564 doi "https://doi.org/10.1016/s0960-5428(06)80032-x" @default.
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