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• W1997069196 abstract "In 1961, Lee and Fisher reported a reliable technique for making a portacaval shunt in the rat that has proven to be reproducible in the hands of many investigators. Sudden diversion of portal blood from the healthy rat liver causes a transient loss in body weight and specific atrophy of the liver in accord with the decrease in total liver blood flow caused by the shunt, but the liver of an Eck fistula rat clearly retains its potential to regenerate. Shuntrelated alterations in metabolic activity and hormone balance have been documented, and appear to be related either to decreased liver blood flow, or to impaired access of the liver to substances that are predominantly present in splanchnic venous blood." @default.
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• W1997069196 date "1974-07-01" @default.
• W1997069196 modified "2023-10-16" @default.
• W1997069196 title "Portal-systemic anastomosis in the rat" @default.
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• W1997069196 doi "https://doi.org/10.1016/0022-4804(74)90168-1" @default.
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