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- W1997084313 abstract "Markers of the immune system were examined in 47 patients with haemophilia A and B who had been treated exclusively with blood products from a population apparently free from acquired immunodeficiency syndrome (AIDS). In haemophilia A the absolute number of T helper cells was depressed, resulting in a reduction in the helper/suppressor ratio in about half the patients. The serum IgG and IgA concentrations were raised and the serum IgG correlated with serum alanine aminotransferase. In haemophilia B, the helper/suppressor ratio was also depressed but this was attributable to a slight increase in the mean suppressor cell number and a slight decrease in the helper cells. These observations suggest that the abnormalities result from transfusion of foreign proteins and not from a specific infective agent and, further, that individuals may differ in susceptibility to the induced disturbances of immunity." @default.
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- W1997084313 date "1984-06-01" @default.
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- W1997084313 title "ABNORMALITIES OF CIRCULATING LYMPHOCYTE SUBSETS IN HAEMOPHILIACS IN AN AIDS-FREE POPULATION" @default.
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- W1997084313 doi "https://doi.org/10.1016/s0140-6736(84)91931-7" @default.
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