FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997114025> ?p ?o ?g. }

• W1997114025 endingPage "199" @default.
• W1997114025 startingPage "194" @default.
• W1997114025 abstract "Purpose Although survival without resection of pulmonary metastases from osteosarcoma is unlikely, not all surgeons agree on an aggressive surgical approach. We have taken an approach to attempt surgical resection if at all feasible regardless of number of metastases and disease-free interval (DFI). This study presents information on long-term follow-up after this aggressive approach to resection. Methods A single-institution retrospective cohort study of osteosarcoma patients younger than 21 years with pulmonary metastases, limited to the contemporary chemotherapeutic period (1980-2000), was conducted. Results In 137 patients, synchronous (23.4%) or metachronous (76.6%) pulmonary nodules were identified. The median follow-up was 2.0 years (5 days to 20.1 years) for all patients. Overall survival among patients who had pulmonary nodules was 40.2% and 22.6% at 3 and 5 years, respectively. Ninety-nine patients underwent attempted pulmonary metastasectomy (mean survival, 33.6 months; 95% confidence interval, 25.1-42.1) and 38 patients did not (mean survival, 10.1 months; 95% confidence interval, 6.5-13.6; P < .001, t test). Characteristics that were associated with an increased likelihood of 5-year overall survival after pulmonary resection were primary tumor necrosis greater than 98% after neoadjuvant chemotherapy (P < .05) and DFI before developing lung metastases more than 1 year (P < .001). No statistically significant difference in overall survival or disease-free survival was found based on the number of pulmonary metastases resected. Characteristics including primary tumor size, site, or extension; chemotherapy; early vs late metastases; unilateral vs bilateral metastases; and resection margins did not significantly affect survival. Conclusions Most patient and tumor characteristics commonly used by surgeons to determine utility of resection of pulmonary metastases among patients with osteosarcoma are not associated with outcome. Biology of the particular tumor (response to preoperative chemotherapy, measured by tumor necrosis percentage, and DFI), as opposed to tumor burden, appears to influence survival more significantly. We would advocate considering repeat pulmonary resection for patients with recurrent metastases from osteosarcoma." @default.
• W1997114025 created "2016-06-24" @default.
• W1997114025 creator A5003536492 @default.
• W1997114025 creator A5007404509 @default.
• W1997114025 creator A5022944335 @default.
• W1997114025 creator A5033655189 @default.
• W1997114025 creator A5036052316 @default.
• W1997114025 creator A5046099119 @default.
• W1997114025 creator A5053714656 @default.
• W1997114025 creator A5063990273 @default.
• W1997114025 creator A5089544107 @default.
• W1997114025 date "2006-01-01" @default.
• W1997114025 modified "2023-10-16" @default.
• W1997114025 title "Long-term survival after aggressive resection of pulmonary metastases among children and adolescents with osteosarcoma" @default.
• W1997114025 cites W1821095830 @default.
• W1997114025 cites W1917704862 @default.
• W1997114025 cites W1954845453 @default.
• W1997114025 cites W1964546638 @default.
• W1997114025 cites W1967023478 @default.
• W1997114025 cites W1969773270 @default.
• W1997114025 cites W1973311536 @default.
• W1997114025 cites W1998191384 @default.
• W1997114025 cites W2001567520 @default.
• W1997114025 cites W2004900202 @default.
• W1997114025 cites W2026104663 @default.
• W1997114025 cites W2030505692 @default.
• W1997114025 cites W2037385810 @default.
• W1997114025 cites W2056439679 @default.
• W1997114025 cites W2069174158 @default.
• W1997114025 cites W2072128072 @default.
• W1997114025 cites W2079450481 @default.
• W1997114025 cites W2082386694 @default.
• W1997114025 cites W2100666869 @default.
• W1997114025 cites W2104070754 @default.
• W1997114025 cites W2127023405 @default.
• W1997114025 cites W2141788705 @default.
• W1997114025 cites W2148077417 @default.
• W1997114025 cites W2222995977 @default.
• W1997114025 doi "https://doi.org/10.1016/j.jpedsurg.2005.10.089" @default.
• W1997114025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16410132" @default.
• W1997114025 hasPublicationYear "2006" @default.
• W1997114025 type Work @default.
• W1997114025 sameAs 1997114025 @default.
• W1997114025 citedByCount "159" @default.
• W1997114025 countsByYear W19971140252012 @default.
• W1997114025 countsByYear W19971140252013 @default.
• W1997114025 countsByYear W19971140252014 @default.
• W1997114025 countsByYear W19971140252015 @default.
• W1997114025 countsByYear W19971140252016 @default.
• W1997114025 countsByYear W19971140252017 @default.
• W1997114025 countsByYear W19971140252018 @default.
• W1997114025 countsByYear W19971140252019 @default.
• W1997114025 countsByYear W19971140252020 @default.
• W1997114025 countsByYear W19971140252021 @default.
• W1997114025 countsByYear W19971140252022 @default.
• W1997114025 countsByYear W19971140252023 @default.
• W1997114025 crossrefType "journal-article" @default.
• W1997114025 hasAuthorship W1997114025A5003536492 @default.
• W1997114025 hasAuthorship W1997114025A5007404509 @default.
• W1997114025 hasAuthorship W1997114025A5022944335 @default.
• W1997114025 hasAuthorship W1997114025A5033655189 @default.
• W1997114025 hasAuthorship W1997114025A5036052316 @default.
• W1997114025 hasAuthorship W1997114025A5046099119 @default.
• W1997114025 hasAuthorship W1997114025A5053714656 @default.
• W1997114025 hasAuthorship W1997114025A5063990273 @default.
• W1997114025 hasAuthorship W1997114025A5089544107 @default.
• W1997114025 hasConcept C121608353 @default.
• W1997114025 hasConcept C126322002 @default.
• W1997114025 hasConcept C141071460 @default.
• W1997114025 hasConcept C142724271 @default.
• W1997114025 hasConcept C167135981 @default.
• W1997114025 hasConcept C2776694085 @default.
• W1997114025 hasConcept C2777714996 @default.
• W1997114025 hasConcept C2777760704 @default.
• W1997114025 hasConcept C2778601017 @default.
• W1997114025 hasConcept C2779013556 @default.
• W1997114025 hasConcept C2780283643 @default.
• W1997114025 hasConcept C44249647 @default.
• W1997114025 hasConcept C71924100 @default.
• W1997114025 hasConcept C72563966 @default.
• W1997114025 hasConceptScore W1997114025C121608353 @default.
• W1997114025 hasConceptScore W1997114025C126322002 @default.
• W1997114025 hasConceptScore W1997114025C141071460 @default.
• W1997114025 hasConceptScore W1997114025C142724271 @default.
• W1997114025 hasConceptScore W1997114025C167135981 @default.
• W1997114025 hasConceptScore W1997114025C2776694085 @default.
• W1997114025 hasConceptScore W1997114025C2777714996 @default.
• W1997114025 hasConceptScore W1997114025C2777760704 @default.
• W1997114025 hasConceptScore W1997114025C2778601017 @default.
• W1997114025 hasConceptScore W1997114025C2779013556 @default.
• W1997114025 hasConceptScore W1997114025C2780283643 @default.
• W1997114025 hasConceptScore W1997114025C44249647 @default.
• W1997114025 hasConceptScore W1997114025C71924100 @default.
• W1997114025 hasConceptScore W1997114025C72563966 @default.
• W1997114025 hasIssue "1" @default.
• W1997114025 hasLocation W19971140251 @default.
• W1997114025 hasLocation W19971140252 @default.
• W1997114025 hasOpenAccess W1997114025 @default.

• next