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- W1997174429 abstract "Dendrotoxin, a lijow molecular weight protein from the venom of Dendroaspis angusticeps , is known to be a potent convulsant that attenuates one type of voltage‐sensitive K + channel in guinea‐pig hippocampus. A biologically active preparation of 125 I‐labelled dendrotoxin has been cross‐linked to its high‐affinity protein acceptor in synaptic plasma membranes from rat cerebral cortex. On SDS gel electrophoresis, a complex with a M r of 72,000 was observed which, assuming one toxin molecule is attached, yields an apparent size of 65,000 for this subunit of the acceptor. Unlike dendrotoxin, low concentrations of β‐bungarotoxin, another pre‐synaptically acitve toxin, do not inhibit its labelling." @default.
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- W1997174429 date "1984-08-20" @default.
- W1997174429 modified "2023-09-25" @default.
- W1997174429 title "Identification by cross‐linking of a neuronal acceptor protein for dendrotoxin, a convulsant polypeptide" @default.
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- W1997174429 doi "https://doi.org/10.1016/0014-5793(84)81088-1" @default.
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