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• W1997177552 abstract "Genetic markers are often used to examine population history. There is considerable debate about the behaviour of molecular clock rates around the population-species transition. Nevertheless, appropriate calibration is critical to any inference regarding the absolute timing and scale of demographic changes. Here, we use a mitochondrial cytochrome b gene genealogy, based entirely on modern sequences and calibrated from recent geophysical events, to date the post-glacial expansion of the Eurasian field vole ( Microtus agrestis ), a widespread temperate mammal species. The phylogeographic structure reflects the subsequent expansion of populations that went through bottlenecks at the time of the Younger Dryas ( ca 12 000 years BP) rather than the Last Glacial Maximum (LGM, ca 24 000 years BP), which is usually seen as the time when present-day patterns were determined. The nucleotide substitution rate that was estimated here, ca 4 × 10 −7 substitutions/site/year, remains extremely high throughout the relevant time frame. Calibration with similarly high population-based substitution rates, rather than long-term rates derived from species divergence times, will show that post-LGM climatic events generated current phylogeographic structure in many other organisms from temperate latitudes." @default.
• W1997177552 created "2016-06-24" @default.
• W1997177552 creator A5001559305 @default.
• W1997177552 creator A5062172255 @default.
• W1997177552 date "2011-04-20" @default.
• W1997177552 modified "2023-09-24" @default.
• W1997177552 title "Post-glacial partitioning of mitochondrial genetic variation in the field vole" @default.
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• W1997177552 doi "https://doi.org/10.1098/rspb.2011.0321" @default.
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