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- W1997182014 abstract "Ultrastructural alterations occurring in hamster cheek pouch epithelium as a result of 7,12-dimethylbenzanthracene (DMBA) applications revealed a marked disturbance in the intercellular relationship of epithelial cells. Widening of the intercellular spaces took place as early as the 2nd day of DMBA applications. Similar changes were observed when a non-carcinogenic irritant (xylene) was applied. It is suggested that such changes may facilitate the penetration of a carcinogen to the stratum germinativum and the underlying connective tissue. The most striking feature observed in the cells obtained from tumour tissue consisted of a peculiar clumping of tonofibrils on the periphery of the cytoplasm, with a concomitant depletion of the tonofibrillar elements from the main portion of the cytoplasm." @default.
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- W1997182014 date "1963-03-01" @default.
- W1997182014 modified "2023-09-24" @default.
- W1997182014 title "Ultrastructural alterations in hamster cheek pouch epithelium in response to a carcinogen" @default.
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- W1997182014 doi "https://doi.org/10.1016/0003-9969(63)90052-9" @default.
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