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- W1997201210 abstract "1. In order to better understand ligand-induced redistribution of membrane receptors and lymphocyte activation in ectothermie vertebrates, flow cytometry was used to monitor the effects of both in vivo acclimation temperature and in vitro assay temperatures on the kinetics of monoclonal antibody-induced membrane immunoglobulin (mIg) capping on channel catfish lymphocytes. 2. It was observed that the kinetics of mIg capping were dependent on in vitro assay temperatures, in vivo acclimation temperatures, and the length of time of in vivo acclimation. In the latter situation in vivo acclimation offish to 27, 22 and 17°C was considered complete after 3 weeks, while acclimation to 12°C required a minimum of 5 weeks. 3. The energies of activation required for mig capping ranged from 33 to 24kcal/mol; lower energies of activation were observed with lower temperature acclimation. 4. It was also noted that the lower energies of activation were associated with concomitant decreases in cellular phospholipid saturated/unsaturated fatty acid ratios. 5. It appears that channel catfish B cell mig capping, presumably a requisite for immune function, can be significantly affected by environmental temperatures; most likely such effects are attributable to changes in plasma membrane viscosities." @default.
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- W1997201210 date "1987-01-01" @default.
- W1997201210 modified "2023-09-26" @default.
- W1997201210 title "Temperature-mediated processes in teleost immunity: the effects of temperature on membrane immunoglobulin capping on channel catfish b lymphocytes" @default.
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- W1997201210 doi "https://doi.org/10.1016/0300-9629(87)90100-9" @default.
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