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- W1997227729 abstract "Certain 1,2,3-triazole derivatives were prepared and tested for their ability to displace [3H]diazepam from bovine brain membranes. From these compounds, the quinolyltriazole derivatives (14, 15, 16, 17) were clearly the most potent, while the naphthyl- and the naphthyridyltriazoles were considerably less active. The p-nitrophenyl derivative (15) was the compound that bound with the highest affinity within the quinolyltriazole compounds class. The replacement of the p-nitrophenyl group with other substituents greatly decreased the binding activity. From a Lineweaver–Burk analysis of 11, it appears that the inhibition is competitive." @default.
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- W1997227729 date "1988-11-01" @default.
- W1997227729 modified "2023-09-23" @default.
- W1997227729 title "Specific Inhibition of Benzodiazepine Receptor Binding by Some 1,2,3-Triazole Derivatives" @default.
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- W1997227729 doi "https://doi.org/10.1002/jps.2600771117" @default.
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