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- W1997241000 abstract "The phosphoramidite 11 was prepared in three steps from methyl 2-mercaptoacetate and demonstrated efficiency in the synthesis of conventional 5‘-/3‘-phosphate/thiophosphate monoester derivatives of 2‘-deoxyribonucleosides and DNA oligonucleotides. Moreover, the use of 11 has enabled the preparation of the dinucleoside phosphorothioate analogue 26 in high yields (>95%) with minimal cleavage (<2%) of the thermolytic thiophosphate protecting group." @default.
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- W1997241000 date "2005-08-23" @default.
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- W1997241000 title "An Efficient Reagent for the Phosphorylation of Deoxyribonucleosides, DNA Oligonucleotides, and Their Thermolytic Analogues" @default.
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- W1997241000 doi "https://doi.org/10.1021/ol0516263" @default.
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