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• W1997277585 abstract "Purpose In this study, osteoblast-like MG-63 cells were cultured on 3 different scaffold types composed of (a) collagen + poly-L-lactic acid (PLLA), (b) collagen + hydroxyapatite (HA; 30°C) or (c) collagen + hydroxyapatite (HA; 37°C) and produced with different porosities. Methods Biomechanical properties of the scaffolds were characterized by tensile strength measurements. Properties of the cell-seeded scaffolds were evaluated with scanning electron microscopy (SEM). Cell adhesion and proliferation capacities were evaluated. Alkaline phosphatase (ALP) levels in media were measured. Transmission electron microscopy (TEM) and histological analyses were used to assess morphological characteristics. Results Our results showed that collagen-based PLLA and HA scaffolds have good cell biocompatibility. MTT test showed that the scaffolds exhibited no cytotoxicity. According to the force and displacement data, collagen + HA at 37°C showed the highest mechanical strength and displacement. Conclusion The results suggest that collagen-based PLLA and HA scaffolds might improve osteoblastic growth in vitro and have biomaterial integration potential in possible therapeutic approaches for future clinical studies." @default.
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• W1997277585 date "2015-01-01" @default.
• W1997277585 modified "2023-10-16" @default.
• W1997277585 title "Biocompatibility of MG-63 Cells on Collagen, Poly-L-Lactic Acid, Hydroxyapatite Scaffolds with Different Parameters" @default.
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• W1997277585 doi "https://doi.org/10.5301/jabfm.5000182" @default.
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