Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997283907> ?p ?o ?g. }
- W1997283907 abstract "The glucocorticoid receptor from rat liver cytosol prepared in 2 ml buffer/g tissue sedimented at approximately 10 S in low salt density gradient centrifugation without molybdate. When the receptor was heated at 25 degrees C, both approximately 10 S and approximately 7 S forms were seen in low salt gradient. The approximately 10 S form was not capable of binding to DNA-cellulose and was stabilized by sodium molybdate, namely it corresponded to untransformed receptor. The approximately 7 S form was capable of binding to DNA-cellulose and regarded as transformed receptor. On the other hand, partially-purified transformed receptor labeled with [3H]dexamethasone-21-mesylate sedimented at approximately 5 S, which migrated as a approximately 94 kDa species in SDS-polyacrylamide gel electrophoresis. The reconstitution analysis of this partially-purified approximately 5 S receptor and liver cytosol, showed the shift to approximately 7 S form. RNase A or T1 converted approximately 7 S transformed form into approximately 5 S but it did not affect approximately 10 S untransformed form. 5-20 mM sodium molybdate also shifted approximately 7 S to approximately 5 S. These results indicate that the approximately 7 S transformed form of the glucocorticoid receptor observed in low salt conditions might be an oligomer, probably including both approximately 5 S steroid-binding component and RNA/ribonucleoprotein, and that molybdate dissociates these interactions in a specific manner." @default.
- W1997283907 created "2016-06-24" @default.
- W1997283907 creator A5013604895 @default.
- W1997283907 creator A5034689721 @default.
- W1997283907 creator A5068174476 @default.
- W1997283907 creator A5071309978 @default.
- W1997283907 creator A5074129968 @default.
- W1997283907 creator A5076268036 @default.
- W1997283907 creator A5085555561 @default.
- W1997283907 date "1987-07-01" @default.
- W1997283907 modified "2023-09-25" @default.
- W1997283907 title "Sodium molybdate converts the RNA-associated transformed, oligomeric form of the glucocorticoid receptor into the transformed, monomeric form" @default.
- W1997283907 cites W143488173 @default.
- W1997283907 cites W1481489488 @default.
- W1997283907 cites W1501075384 @default.
- W1997283907 cites W1505589424 @default.
- W1997283907 cites W1534815799 @default.
- W1997283907 cites W1541332557 @default.
- W1997283907 cites W1570663378 @default.
- W1997283907 cites W1579538028 @default.
- W1997283907 cites W1584477524 @default.
- W1997283907 cites W1611482599 @default.
- W1997283907 cites W1690297938 @default.
- W1997283907 cites W178378932 @default.
- W1997283907 cites W1896307881 @default.
- W1997283907 cites W1906197854 @default.
- W1997283907 cites W1913466562 @default.
- W1997283907 cites W1965176151 @default.
- W1997283907 cites W1977613095 @default.
- W1997283907 cites W1984735828 @default.
- W1997283907 cites W2001139153 @default.
- W1997283907 cites W2002931164 @default.
- W1997283907 cites W2003514090 @default.
- W1997283907 cites W2004075892 @default.
- W1997283907 cites W2005996033 @default.
- W1997283907 cites W2007169317 @default.
- W1997283907 cites W2018531293 @default.
- W1997283907 cites W2018632980 @default.
- W1997283907 cites W2022411824 @default.
- W1997283907 cites W2024745769 @default.
- W1997283907 cites W2028234426 @default.
- W1997283907 cites W2041052345 @default.
- W1997283907 cites W2046201653 @default.
- W1997283907 cites W2061208799 @default.
- W1997283907 cites W2063014237 @default.
- W1997283907 cites W2063795328 @default.
- W1997283907 cites W2064345521 @default.
- W1997283907 cites W2068921569 @default.
- W1997283907 cites W2100837269 @default.
- W1997283907 cites W2208707498 @default.
- W1997283907 cites W2211434907 @default.
- W1997283907 cites W4293247451 @default.
- W1997283907 doi "https://doi.org/10.1016/0022-4731(87)90116-6" @default.
- W1997283907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2441143" @default.
- W1997283907 hasPublicationYear "1987" @default.
- W1997283907 type Work @default.
- W1997283907 sameAs 1997283907 @default.
- W1997283907 citedByCount "5" @default.
- W1997283907 crossrefType "journal-article" @default.
- W1997283907 hasAuthorship W1997283907A5013604895 @default.
- W1997283907 hasAuthorship W1997283907A5034689721 @default.
- W1997283907 hasAuthorship W1997283907A5068174476 @default.
- W1997283907 hasAuthorship W1997283907A5071309978 @default.
- W1997283907 hasAuthorship W1997283907A5074129968 @default.
- W1997283907 hasAuthorship W1997283907A5076268036 @default.
- W1997283907 hasAuthorship W1997283907A5085555561 @default.
- W1997283907 hasConcept C104317684 @default.
- W1997283907 hasConcept C10879258 @default.
- W1997283907 hasConcept C132946820 @default.
- W1997283907 hasConcept C170493617 @default.
- W1997283907 hasConcept C178790620 @default.
- W1997283907 hasConcept C179104552 @default.
- W1997283907 hasConcept C181199279 @default.
- W1997283907 hasConcept C185592680 @default.
- W1997283907 hasConcept C2775981058 @default.
- W1997283907 hasConcept C2778205819 @default.
- W1997283907 hasConcept C2780642029 @default.
- W1997283907 hasConcept C537181965 @default.
- W1997283907 hasConcept C55493867 @default.
- W1997283907 hasConcept C59493245 @default.
- W1997283907 hasConcept C67705224 @default.
- W1997283907 hasConcept C7623868 @default.
- W1997283907 hasConcept C98539663 @default.
- W1997283907 hasConceptScore W1997283907C104317684 @default.
- W1997283907 hasConceptScore W1997283907C10879258 @default.
- W1997283907 hasConceptScore W1997283907C132946820 @default.
- W1997283907 hasConceptScore W1997283907C170493617 @default.
- W1997283907 hasConceptScore W1997283907C178790620 @default.
- W1997283907 hasConceptScore W1997283907C179104552 @default.
- W1997283907 hasConceptScore W1997283907C181199279 @default.
- W1997283907 hasConceptScore W1997283907C185592680 @default.
- W1997283907 hasConceptScore W1997283907C2775981058 @default.
- W1997283907 hasConceptScore W1997283907C2778205819 @default.
- W1997283907 hasConceptScore W1997283907C2780642029 @default.
- W1997283907 hasConceptScore W1997283907C537181965 @default.
- W1997283907 hasConceptScore W1997283907C55493867 @default.
- W1997283907 hasConceptScore W1997283907C59493245 @default.
- W1997283907 hasConceptScore W1997283907C67705224 @default.
- W1997283907 hasConceptScore W1997283907C7623868 @default.
- W1997283907 hasConceptScore W1997283907C98539663 @default.