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- W1997291283 endingPage "35" @default.
- W1997291283 startingPage "35" @default.
- W1997291283 abstract "Background: Transcatheter aortic valve implantation (TAVI) has emerged as an important treatment for patients with severe symptomatic aortic stenosis who are at high operative risk, but accurate estimates of serious adverse effects in contemporary practice are not available. Purpose: To quantify the adverse effects associated with TAVI, and to evaluate whether the type of transcatheter valve and the route of valve implantation are associated with differences in adverse outcomes. Data Source: PubMed to 5 May 2012. Study Selection: All studies that included at least 100 patients who had TAVI and reported at least 1 outcome of interest. Data Extraction: Two reviewers abstracted the data independently. A random-effects model was used to combine data on adverse outcomes and conduct stratified analyses. Data Synthesis: A total of 49 studies enrolling 16 063 patients met the inclusion criteria. Overall 30-day and 1-year survival after TAVI were 91.9% (95% CI, 91.1% to 92.8%) and 79.2% (CI, 76.9% to 81.4%), respectively. Heart block requiring permanent pacemaker implantation was the most common adverse outcome (13.1%) and was 5 times more common with the CoreValve (Medtronic, Minneapolis, Minnesota) than the Sapien valve (Edwards Lifesciences, Irving, California) implanted using the transarterial route (25.2% vs. 5.0%, respectively). The overall rate of vascular complications was 10.4% and was highest with transarterial implantation of the Sapien valve (22.3%). Acute renal failure requiring renal replacement therapy was the third most common complication, occurring in 4.9% of patients. Limitation: Rates of major vascular complications may be overestimated owing to rapidly evolving TAVI technology. Conclusion: The most common adverse effects associated with TAVI are heart block, vascular complications, and renal failure. The type of transcatheter valve and the route of implantation are associated with observed variations in the risks for some adverse effects. Primary Funding Source: Heart and Stroke Foundation of Canada." @default.
- W1997291283 created "2016-06-24" @default.
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- W1997291283 date "2013-01-01" @default.
- W1997291283 modified "2023-10-17" @default.
- W1997291283 title "Adverse Effects Associated With Transcatheter Aortic Valve Implantation" @default.
- W1997291283 cites W135480334 @default.
- W1997291283 cites W1483572370 @default.
- W1997291283 cites W1489391104 @default.
- W1997291283 cites W1560998933 @default.
- W1997291283 cites W1576837341 @default.
- W1997291283 cites W189624128 @default.
- W1997291283 cites W1965255505 @default.
- W1997291283 cites W1967046314 @default.
- W1997291283 cites W1971084835 @default.
- W1997291283 cites W1973814658 @default.
- W1997291283 cites W1974867432 @default.
- W1997291283 cites W1975093525 @default.
- W1997291283 cites W197696800 @default.
- W1997291283 cites W1981040027 @default.
- W1997291283 cites W1986142308 @default.
- W1997291283 cites W1987880059 @default.
- W1997291283 cites W1988635910 @default.
- W1997291283 cites W1990033097 @default.
- W1997291283 cites W1992282865 @default.
- W1997291283 cites W1995092812 @default.
- W1997291283 cites W2001905888 @default.
- W1997291283 cites W2008616637 @default.
- W1997291283 cites W2008707152 @default.
- W1997291283 cites W2009332265 @default.
- W1997291283 cites W2011968584 @default.
- W1997291283 cites W2012690369 @default.
- W1997291283 cites W2013231741 @default.
- W1997291283 cites W2014620945 @default.
- W1997291283 cites W2014730986 @default.
- W1997291283 cites W2014766956 @default.
- W1997291283 cites W2018261516 @default.
- W1997291283 cites W2018696687 @default.
- W1997291283 cites W2022123127 @default.
- W1997291283 cites W2022851384 @default.
- W1997291283 cites W2024543886 @default.
- W1997291283 cites W2037447718 @default.
- W1997291283 cites W2037874680 @default.
- W1997291283 cites W2044996522 @default.
- W1997291283 cites W2047956426 @default.
- W1997291283 cites W205039322 @default.
- W1997291283 cites W2052085643 @default.
- W1997291283 cites W2054488835 @default.
- W1997291283 cites W2055123131 @default.
- W1997291283 cites W2055178919 @default.
- W1997291283 cites W2057945112 @default.
- W1997291283 cites W2058931385 @default.
- W1997291283 cites W2059689582 @default.
- W1997291283 cites W2059825413 @default.
- W1997291283 cites W2061709095 @default.
- W1997291283 cites W2061856082 @default.
- W1997291283 cites W2068491095 @default.
- W1997291283 cites W2069784595 @default.
- W1997291283 cites W2072786761 @default.
- W1997291283 cites W2076331982 @default.
- W1997291283 cites W2083423510 @default.
- W1997291283 cites W2085010218 @default.
- W1997291283 cites W2086088719 @default.
- W1997291283 cites W2086093281 @default.
- W1997291283 cites W2086740260 @default.
- W1997291283 cites W2086917212 @default.
- W1997291283 cites W2094265494 @default.
- W1997291283 cites W2096204162 @default.
- W1997291283 cites W2096726239 @default.
- W1997291283 cites W2102352001 @default.
- W1997291283 cites W2107328434 @default.
- W1997291283 cites W2110226194 @default.
- W1997291283 cites W2110884945 @default.
- W1997291283 cites W2114756102 @default.
- W1997291283 cites W2116163173 @default.
- W1997291283 cites W2124421059 @default.
- W1997291283 cites W2126080365 @default.
- W1997291283 cites W2128190995 @default.
- W1997291283 cites W2129975031 @default.
- W1997291283 cites W2130508139 @default.
- W1997291283 cites W2134152311 @default.
- W1997291283 cites W2138804833 @default.
- W1997291283 cites W2139168999 @default.
- W1997291283 cites W2140033602 @default.
- W1997291283 cites W2140962775 @default.
- W1997291283 cites W2142481232 @default.
- W1997291283 cites W2144966583 @default.
- W1997291283 cites W2146792142 @default.
- W1997291283 cites W2147594989 @default.
- W1997291283 cites W2149609916 @default.