FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997301708> ?p ?o ?g. }

• W1997301708 endingPage "3002" @default.
• W1997301708 startingPage "2991" @default.
• W1997301708 abstract "The molecular programs that specify progenitors in the dorsal spinal cord remain poorly defined. The homeodomain transcription factor Gsh2 is expressed in the progenitors of three dorsal interneuron subtypes, dI3, dI4 and dI5 neurons, whereas Gsh1 is only expressed in dI4 and dI5 progenitors. Mice lacking Gsh2 exhibit a selective loss of dI3 interneurons that is accompanied by an expansion of the dI2 progenitor domain. In Gsh2mutant embryos, expression of the proneural bHLH protein Mash1 is downregulated in dI3 neural progenitors, with Mash1 mutants exhibiting a concordant reduction in dI3 neurons. Conversely, overexpression of Gsh2 and Mash1 leads to the ectopic production of dI3 neurons and a concomitant repression of Ngn1 expression. Our results provide evidence that genetic interactions involving repression of Ngn1 by Gsh2promote the differentiation of dI3 neurons from class A progenitors." @default.
• W1997301708 created "2016-06-24" @default.
• W1997301708 creator A5017111418 @default.
• W1997301708 creator A5044896974 @default.
• W1997301708 creator A5051660914 @default.
• W1997301708 creator A5059664782 @default.
• W1997301708 creator A5090823484 @default.
• W1997301708 date "2005-07-01" @default.
• W1997301708 modified "2023-10-18" @default.
• W1997301708 title "Gsh2 is required for the repression of Ngn1 and specification of dorsal interneuron fate in the spinal cord" @default.
• W1997301708 cites W156202311 @default.
• W1997301708 cites W1884216083 @default.
• W1997301708 cites W1894858966 @default.
• W1997301708 cites W1968707675 @default.
• W1997301708 cites W1970795696 @default.
• W1997301708 cites W1979881566 @default.
• W1997301708 cites W1983983875 @default.
• W1997301708 cites W2004257326 @default.
• W1997301708 cites W2006047257 @default.
• W1997301708 cites W2006169062 @default.
• W1997301708 cites W2009283506 @default.
• W1997301708 cites W2009828482 @default.
• W1997301708 cites W2013180460 @default.
• W1997301708 cites W2014479208 @default.
• W1997301708 cites W2020444846 @default.
• W1997301708 cites W2026682189 @default.
• W1997301708 cites W2034682531 @default.
• W1997301708 cites W2038998122 @default.
• W1997301708 cites W2040773128 @default.
• W1997301708 cites W2055190734 @default.
• W1997301708 cites W2055329431 @default.
• W1997301708 cites W2076499613 @default.
• W1997301708 cites W2081235375 @default.
• W1997301708 cites W2082785396 @default.
• W1997301708 cites W2082807347 @default.
• W1997301708 cites W2083242763 @default.
• W1997301708 cites W2086838437 @default.
• W1997301708 cites W2098867949 @default.
• W1997301708 cites W2109597876 @default.
• W1997301708 cites W2109899567 @default.
• W1997301708 cites W2112066508 @default.
• W1997301708 cites W2120981619 @default.
• W1997301708 cites W2122199698 @default.
• W1997301708 cites W2122506917 @default.
• W1997301708 cites W2123933036 @default.
• W1997301708 cites W2128650008 @default.
• W1997301708 cites W2136602932 @default.
• W1997301708 cites W2139909837 @default.
• W1997301708 cites W2144274759 @default.
• W1997301708 cites W2149278002 @default.
• W1997301708 cites W2149519740 @default.
• W1997301708 cites W2155214369 @default.
• W1997301708 cites W2155291163 @default.
• W1997301708 cites W2158499654 @default.
• W1997301708 cites W244331836 @default.
• W1997301708 cites W4248042899 @default.
• W1997301708 doi "https://doi.org/10.1242/dev.01878" @default.
• W1997301708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15930101" @default.
• W1997301708 hasPublicationYear "2005" @default.
• W1997301708 type Work @default.
• W1997301708 sameAs 1997301708 @default.
• W1997301708 citedByCount "49" @default.
• W1997301708 countsByYear W19973017082012 @default.
• W1997301708 countsByYear W19973017082013 @default.
• W1997301708 countsByYear W19973017082014 @default.
• W1997301708 countsByYear W19973017082015 @default.
• W1997301708 countsByYear W19973017082016 @default.
• W1997301708 countsByYear W19973017082017 @default.
• W1997301708 countsByYear W19973017082018 @default.
• W1997301708 countsByYear W19973017082019 @default.
• W1997301708 countsByYear W19973017082020 @default.
• W1997301708 crossrefType "journal-article" @default.
• W1997301708 hasAuthorship W1997301708A5017111418 @default.
• W1997301708 hasAuthorship W1997301708A5044896974 @default.
• W1997301708 hasAuthorship W1997301708A5051660914 @default.
• W1997301708 hasAuthorship W1997301708A5059664782 @default.
• W1997301708 hasAuthorship W1997301708A5090823484 @default.
• W1997301708 hasBestOaLocation W19973017081 @default.
• W1997301708 hasConcept C104317684 @default.
• W1997301708 hasConcept C105702510 @default.
• W1997301708 hasConcept C121587040 @default.
• W1997301708 hasConcept C150194340 @default.
• W1997301708 hasConcept C15729860 @default.
• W1997301708 hasConcept C169760540 @default.
• W1997301708 hasConcept C17077164 @default.
• W1997301708 hasConcept C186310378 @default.
• W1997301708 hasConcept C201750760 @default.
• W1997301708 hasConcept C2779296341 @default.
• W1997301708 hasConcept C2780775167 @default.
• W1997301708 hasConcept C28328180 @default.
• W1997301708 hasConcept C54355233 @default.
• W1997301708 hasConcept C86339819 @default.
• W1997301708 hasConcept C86803240 @default.
• W1997301708 hasConcept C95444343 @default.
• W1997301708 hasConcept C97037327 @default.
• W1997301708 hasConceptScore W1997301708C104317684 @default.
• W1997301708 hasConceptScore W1997301708C105702510 @default.
• W1997301708 hasConceptScore W1997301708C121587040 @default.

• next