Matches in SemOpenAlex for { <https://semopenalex.org/work/W1997337296> ?p ?o ?g. }
- W1997337296 endingPage "1412" @default.
- W1997337296 startingPage "1404" @default.
- W1997337296 abstract "Abstract The aim of this study was to evaluate the photodynamic effect of Sinoporphyrin sodium ( DVDMS ). In this study, Eca‐109 cells were treated with DVDMS (5 μg mL −1 ) and subjected to photodynamic therapy ( PDT ). The uptake and subcellular localization of DVDMS were monitored by flow cytometry and confocal microscopy. The phototoxicity of DVDMS was studied by MTT assay. The morphological changes were observed by scanning electron microscopy ( SEM ). DNA damage, reactive oxygen species ( ROS ) generation and mitochondria membrane potential ( MMP ) changes were analyzed by flow cytometry. Studies demonstrated maximal uptake of DVDMS occurred within 3 h, with a mitochondrial subcellular localization. MTT assays displayed that DVDMS could be effectively activated by light and the phototoxicity was much higher than photofrin under the same conditions. In addition, SEM observation indicated that cells were seriously damaged after PDT treatment. Furthermore, activation of DVDMS resulted in significant increases in ROS production. The generated ROS played an important role in the phototoxicity of DVDMS . DVDMS ‐mediated PDT ( DVDMS ‐ PDT ) also induced DNA damage and MMP loss. It is demonstrated that DVDMS ‐mediated PDT is an effective approach on cell proliferation inhibition of Eca‐109 cells." @default.
- W1997337296 created "2016-06-24" @default.
- W1997337296 creator A5012440657 @default.
- W1997337296 creator A5012788495 @default.
- W1997337296 creator A5016038041 @default.
- W1997337296 creator A5022274692 @default.
- W1997337296 creator A5029035185 @default.
- W1997337296 creator A5039929407 @default.
- W1997337296 creator A5048269616 @default.
- W1997337296 creator A5084688862 @default.
- W1997337296 date "2014-10-07" @default.
- W1997337296 modified "2023-10-03" @default.
- W1997337296 title "Antitumor Effect of Sinoporphyrin Sodium-Mediated Photodynamic Therapy on Human Esophageal Cancer Eca-109 Cells" @default.
- W1997337296 cites W124123785 @default.
- W1997337296 cites W140521660 @default.
- W1997337296 cites W1487084472 @default.
- W1997337296 cites W169027326 @default.
- W1997337296 cites W1759964073 @default.
- W1997337296 cites W183685483 @default.
- W1997337296 cites W1954387510 @default.
- W1997337296 cites W1956520547 @default.
- W1997337296 cites W1972553524 @default.
- W1997337296 cites W1974359427 @default.
- W1997337296 cites W1979798962 @default.
- W1997337296 cites W1980046312 @default.
- W1997337296 cites W1986072252 @default.
- W1997337296 cites W1987531894 @default.
- W1997337296 cites W1988272953 @default.
- W1997337296 cites W1998537863 @default.
- W1997337296 cites W2016885670 @default.
- W1997337296 cites W2023542615 @default.
- W1997337296 cites W2029921133 @default.
- W1997337296 cites W2030088047 @default.
- W1997337296 cites W2038237440 @default.
- W1997337296 cites W2039440815 @default.
- W1997337296 cites W2040172928 @default.
- W1997337296 cites W2043561990 @default.
- W1997337296 cites W2046295314 @default.
- W1997337296 cites W2051899566 @default.
- W1997337296 cites W2055307321 @default.
- W1997337296 cites W2059884354 @default.
- W1997337296 cites W2060877726 @default.
- W1997337296 cites W2062525679 @default.
- W1997337296 cites W2063012524 @default.
- W1997337296 cites W2072225623 @default.
- W1997337296 cites W2073514222 @default.
- W1997337296 cites W2080710543 @default.
- W1997337296 cites W2091420999 @default.
- W1997337296 cites W2103028069 @default.
- W1997337296 cites W2107744999 @default.
- W1997337296 cites W2131408793 @default.
- W1997337296 cites W2135745334 @default.
- W1997337296 cites W2157703656 @default.
- W1997337296 cites W2165232616 @default.
- W1997337296 cites W2211216395 @default.
- W1997337296 cites W2323780697 @default.
- W1997337296 cites W2953245479 @default.
- W1997337296 cites W4211024586 @default.
- W1997337296 cites W51227804 @default.
- W1997337296 cites W1967676418 @default.
- W1997337296 doi "https://doi.org/10.1111/php.12333" @default.
- W1997337296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25142812" @default.
- W1997337296 hasPublicationYear "2014" @default.
- W1997337296 type Work @default.
- W1997337296 sameAs 1997337296 @default.
- W1997337296 citedByCount "23" @default.
- W1997337296 countsByYear W19973372962015 @default.
- W1997337296 countsByYear W19973372962016 @default.
- W1997337296 countsByYear W19973372962017 @default.
- W1997337296 countsByYear W19973372962018 @default.
- W1997337296 countsByYear W19973372962019 @default.
- W1997337296 countsByYear W19973372962020 @default.
- W1997337296 countsByYear W19973372962021 @default.
- W1997337296 countsByYear W19973372962022 @default.
- W1997337296 countsByYear W19973372962023 @default.
- W1997337296 crossrefType "journal-article" @default.
- W1997337296 hasAuthorship W1997337296A5012440657 @default.
- W1997337296 hasAuthorship W1997337296A5012788495 @default.
- W1997337296 hasAuthorship W1997337296A5016038041 @default.
- W1997337296 hasAuthorship W1997337296A5022274692 @default.
- W1997337296 hasAuthorship W1997337296A5029035185 @default.
- W1997337296 hasAuthorship W1997337296A5039929407 @default.
- W1997337296 hasAuthorship W1997337296A5048269616 @default.
- W1997337296 hasAuthorship W1997337296A5084688862 @default.
- W1997337296 hasConcept C143425029 @default.
- W1997337296 hasConcept C153911025 @default.
- W1997337296 hasConcept C178790620 @default.
- W1997337296 hasConcept C185592680 @default.
- W1997337296 hasConcept C190283241 @default.
- W1997337296 hasConcept C202751555 @default.
- W1997337296 hasConcept C20639190 @default.
- W1997337296 hasConcept C2779178360 @default.
- W1997337296 hasConcept C2780783641 @default.
- W1997337296 hasConcept C2781323092 @default.
- W1997337296 hasConcept C48349386 @default.
- W1997337296 hasConcept C502942594 @default.
- W1997337296 hasConcept C552990157 @default.
- W1997337296 hasConcept C553184892 @default.