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- W1997337913 abstract "The persistence of cells with the capacity to differentiate for haemolysin formation has been examined in erythrocyte-tolerant rats transfused with lymphocytes from normal rats. Following the transfer of untreated thoracic duct lymphocytes, plaque-forming ceil precursors could be recovered from the host's spleen during the first three days, although plaque-forming cells themselves failed to appear at any time. It is suggested that the sudden disappearance of antibody-forming cell precursors reflects the induction of immunological tolerance in the transfused lymphocytes or their progeny. When lymphocytes which have been antigenically stimulated in vitro are transferred to tolerant hosts, large numbers of antibody-forming cell precursors can be recovered from the host spleens during the third week after transfer. This implies that, if the disappearance of precursor cells from transferred populations of unstimulated lymphocytes represents the induction of tolerance, this state is less readily induced in antigenically stimulated cells." @default.
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- W1997337913 date "1970-08-01" @default.
- W1997337913 modified "2023-09-23" @default.
- W1997337913 title "THE IMMUNOLOGICAL CAPACITY OF LYMPHOCYTES FROM NORMAL DONORS AFTER THEIR TRANSFER TO RATS TOLERANT OF SHEEP ERYTHROCYTES" @default.
- W1997337913 doi "https://doi.org/10.1038/icb.1970.39" @default.
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