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- W1997349734 abstract "Use of the Neodymium: yttrium -aluminum -garnet (Nd:YAG) laser to recanalize stenosed arteries may require delivery of the beam through blood. To assess the degree of hemolysis and debris formation, 54 samples of citrated whole blood were exposed to Nd:YAG laser radiation of varying powers (10, 20 and 30 watts) and duration (1, 2.5 and 5 seconds). Compared to control samples which were not subjected to laser light, there was no significant decrease in hematocrit (41 to 40.5 ± 5%), hemoglobin concentration (13.8 to 13.8 ± .06 g/lOO ml), or increase in “free” hemoglobin concentration. Debris weight (from .45 ± .002 to .45 ± .002 mg), as well as the white blood cell count, was also not significantly changed (from 5,400 to 5,200 ± 240 WBC/cm). Light microscopy examination of debris from samples of whole blood, washed erythrocytes, and platelet-rich plasma subjected to the laser at 30 watts for five seconds failed to demonstrate the presence of membrane denaturation of blood elements, as compared with the morphologic changes observed in whole blood samples exposed to a “hot tip” rather than Nd:YAG laser radiation. Nd:YAG laser can be used intravascularly without fear of hemolysis or debris “micro-embolizatlon” up to a power of 30 watts for five seconds. Use of the Neodymium: yttrium -aluminum -garnet (Nd:YAG) laser to recanalize stenosed arteries may require delivery of the beam through blood. To assess the degree of hemolysis and debris formation, 54 samples of citrated whole blood were exposed to Nd:YAG laser radiation of varying powers (10, 20 and 30 watts) and duration (1, 2.5 and 5 seconds). Compared to control samples which were not subjected to laser light, there was no significant decrease in hematocrit (41 to 40.5 ± 5%), hemoglobin concentration (13.8 to 13.8 ± .06 g/lOO ml), or increase in “free” hemoglobin concentration. Debris weight (from .45 ± .002 to .45 ± .002 mg), as well as the white blood cell count, was also not significantly changed (from 5,400 to 5,200 ± 240 WBC/cm). Light microscopy examination of debris from samples of whole blood, washed erythrocytes, and platelet-rich plasma subjected to the laser at 30 watts for five seconds failed to demonstrate the presence of membrane denaturation of blood elements, as compared with the morphologic changes observed in whole blood samples exposed to a “hot tip” rather than Nd:YAG laser radiation. Nd:YAG laser can be used intravascularly without fear of hemolysis or debris “micro-embolizatlon” up to a power of 30 watts for five seconds." @default.
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- W1997349734 date "1988-01-01" @default.
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- W1997349734 title "In Vitro Effects of Nd:YAG Laser Radiation on Blood: A Quantitative and Morphologic Analysis" @default.
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- W1997349734 doi "https://doi.org/10.1016/s0890-5096(06)60780-2" @default.
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